LOCUS       c00035_HRGM_G..       25231 bp    DNA     linear   UNK 04-JUL-2020
DEFINITION  Genus species strain strain.
ACCESSION   c00035_HRGM_G..
VERSION     c00035_HRGM_G..
KEYWORDS    .
SOURCE      Genus species
ORGANISM  Genus species Unclassified.
.
COMMENT     Annotated using prokka 1.14.5 from
https://github.com/tseemann/prokka.
##antiSMASH-Data-START##
Version      :: 5.1.2
Run date     :: 2020-07-06 13:58:48
Original ID  :: HRGM_Genome_0011_47
NOTE: This is a single cluster extracted from a larger record!
Orig. start  :: 0
Orig. end    :: 25231
##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
protocluster    1..25231
/aStool="rule-based-clusters"
/contig_edge="True"
/core_location="[1659:5231]"
/cutoff="20000"
/detection_rule="(APE_KS1 or APE_KS2)"
/neighbourhood="20000"
/product="arylpolyene"
/protocluster_number="1"
/tool="antismash"
proto_core      1660..5231
/aStool="rule-based-clusters"
/tool="antismash"
/cutoff="20000"
/detection_rule="(APE_KS1 or APE_KS2)"
/neighbourhood="20000"
/product="arylpolyene"
/protocluster_number="1"
cand_cluster    1..25231
/candidate_cluster_number="1"
/contig_edge="True"
/detection_rules="(APE_KS1 or APE_KS2)"
/kind="single"
/product="arylpolyene"
/protoclusters="1"
/tool="antismash"
region          1..25231
/candidate_cluster_numbers="1"
/contig_edge="True"
/product="arylpolyene"
/region_number="1"
/rules="(APE_KS1 or APE_KS2)"
/tool="antismash"
CDS             90..770
/codon_start=1
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01182"
/product="hypothetical protein"
/transl_table=11
/translation="MLAGELLKSHFAKFDLVAVLSKFLEQSHFDKEKFGLLKQNNFKIL
DKNIKQEIVGTAGFKEFFDEKFRGFLCELMQSRVLIVSGKEYKFSELEIYTCFDANTYK
RQCEAGEIYFHNFGFDISFKSDLSLYGGVLVRSLKPLNGQNFIFGPRKCALHILNSKMS
NLNFDLKEADFRKDGITFTPRIRSFGDENQQKNDCLRAFTAEFEKALEFDENYKKRLNA
YKKG"
CDS             751..1272
/codon_start=1
/gene_functions="biosynthetic-additional (smcogs)
SMCOG1012:4'-phosphopantetheinyl transferase (Score: 57;
E-value: 2.8e-17)"
/gene_kind="biosynthetic-additional"
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01183"
/product="hypothetical protein"
/transl_table=11
/translation="MPIKRGEIHLSISFCGEKFSPKMLDKKDRRKLKKYPNLIKQNSFK
ISRYLKFKAKMRGKICLSHKENIAVLVISKEKIGVDVEELKQRNFDAIASFCFTKEESK
ILANAKDKTQKFYEIYTAKEAILKLKNLSFSDLGTTNYDEMAKRYLIINNSFIICLAFK
QCKDIIIKLL"
CDS             1296..1673
/codon_start=1
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01184"
/product="hypothetical protein"
/transl_table=11
/translation="MLIKKIVIILAISLFALGCAKKFDTPQMVDFDLKTFKVSSSKGLL
LLYVQNSKNEYKFSLVNALGAPEARRLLKDGSFKNLGFLPPNSAYNELFIKVLEMIKDE
KSEQKFMIDDQYYEVESVDLR"
CDS             1660..2826
/EC_number="2.3.1.179"
/NRPS_PKS="Domain: PKS_KS(Iterative-KS) (45-386). E-value:
1.8e-37. Score: 121.0. Matches aSDomain:
nrpspksdomains_HRGM_Genome_0011_CDS_01185_PKS_KS.1"
/NRPS_PKS="type: PKS/NRPS-like protein"
/codon_start=1
/db_xref="COG:COG0304"
/gene="fabF_1"
/gene_functions="biosynthetic (rule-based-clusters)
arylpolyene: APE_KS2"
/gene_functions="biosynthetic-additional (smcogs)
SMCOG1022:Beta-ketoacyl synthase (Score: 193.9; E-value:
8e-59)"
/gene_kind="biosynthetic"
/inference="ab initio prediction:Prodigal:002006"
/inference="similar to AA sequence:UniProtKB:Q83E37"
/locus_tag="HRGM_Genome_0011_CDS_01185"
/product="3-oxoacyl-[acyl-carrier-protein] synthase 2"
/sec_met_domain="APE_KS2 (E-value: 1.3e-134, bitscore:
442.8, seeds: 16, tool: rule-based-clusters)"
/transl_table=11
/translation="MIYVSKPAIISAAGSSCDENLSSLLSGKRFLSLSSEFHPENKFLV
AKFDKALPEFAKKTKEHFKTRTNALLLNTLLELDDEIKRAIKKFGKSRVGVILGTTTSG
IEENFWTFKEYIKTEIFDKSKFGIDRNCLANVTEFVTEFYGLEGPSFCVSTACTSGVKA
IIEAQRLIKSDICDAVICGGVDSLNTLTINGFNSLSILSQKPSQPFSKNREGINIGEGA
GLFLLSRDQISDVIVAGSASNCDAFHMTQPDFSAKMAICCIEEALKKADMRGVDYVNLH
GTGTQANDKMEAKAVNLTLGFAYASSLKPQIGHTLGAAGAIESAICSMLCMEENSTLPP
HVYDGAYDESLEAINLVKSGTKFDVKTAMSLSFAFGGDNAAIIFKRVR"
aSDomain        1795..2817
/ASF="found active site histidines: True"
/aSDomain="PKS_KS"
/aSTool="nrps_pks_domains"
/database="nrpspksdomains.hmm"
/detection="hmmscan"
/domain_id="nrpspksdomains_HRGM_Genome_0011_CDS_01185_PKS_
KS.1"
/evalue="1.80E-37"
/label="HRGM_Genome_0011_CDS_01185_PKS_KS.1"
/locus_tag="HRGM_Genome_0011_CDS_01185"
/protein_end="386"
/protein_start="45"
/score="121.0"
/tool="antismash"
/translation="AKFDKALPEFAKKTKEHFKTRTNALLLNTLLELDDEIKRAIKKFG
KSRVGVILGTTTSGIEENFWTFKEYIKTEIFDKSKFGIDRNCLANVTEFVTEFYGLEGP
SFCVSTACTSGVKAIIEAQRLIKSDICDAVICGGVDSLNTLTINGFNSLSILSQKPSQP
FSKNREGINIGEGAGLFLLSRDQISDVIVAGSASNCDAFHMTQPDFSAKMAICCIEEAL
KKADMRGVDYVNLHGTGTQANDKMEAKAVNLTLGFAYASSLKPQIGHTLGAAGAIESAI
CSMLCMEENSTLPPHVYDGAYDESLEAINLVKSGTKFDVKTAMSLSFAFGGDNAAIIFK
RV"
aSModule        1795..2817
/domains="nrpspksdomains_HRGM_Genome_0011_CDS_01185_PKS_KS
.1"
/incomplete
/iterative
/locus_tags="HRGM_Genome_0011_CDS_01185"
/tool="antismash"
/type="pks"
CDS_motif       2101..2145
/aSTool="nrps_pks_domains"
/database="abmotifs"
/detection="hmmscan"
/domain_id="nrpspksmotif_HRGM_Genome_0011_CDS_01185_0001"
/evalue="4.20E-03"
/label="PKSI-KS_m3"
/locus_tag="HRGM_Genome_0011_CDS_01185"
/protein_end="162"
/protein_start="147"
/score="9.9"
/tool="antismash"
/translation="GPSFCVSTACTSGVKA"
CDS_motif       2737..2778
/aSTool="nrps_pks_domains"
/database="abmotifs"
/detection="hmmscan"
/domain_id="nrpspksmotif_HRGM_Genome_0011_CDS_01185_0002"
/evalue="1.30E+01"
/label="PKSI-KS_m3"
/locus_tag="HRGM_Genome_0011_CDS_01185"
/protein_end="373"
/protein_start="359"
/score="-0.4"
/tool="antismash"
/translation="GTKFDVKTAMSLSFA"
CDS             2826..3266
/codon_start=1
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01186"
/product="hypothetical protein"
/transl_table=11
/translation="MISDYLPHSSAITLIDEILEFTPCESIKVRSVINEQTPFLEDGKF
YMQKAIEMMAQSLGVYDSKMRELRGEKAIFGFLLGSRKFEIFRPYFKVGDEIVIVSKCS
IQDESGFGVYDSELFVNGELGARTVLNVMSPDEEFVKKALSE"
aSDomain        3274..3714
/aSDomain="PKS_KR"
/aSTool="nrps_pks_domains"
/database="nrpspksdomains.hmm"
/detection="hmmscan"
/domain_id="nrpspksdomains_HRGM_Genome_0011_CDS_01187_PKS_
KR.1"
/evalue="4.70E-18"
/label="HRGM_Genome_0011_CDS_01187_PKS_KR.1"
/locus_tag="HRGM_Genome_0011_CDS_01187"
/protein_end="147"
/protein_start="0"
/score="57.5"
/specificity="KR activity: inactive"
/specificity="KR stereochemistry: C2"
/tool="antismash"
/translation="MITGSSRGIGASIARHLANKYEVVLHARSKSDELLKMASELGAKF
LTFDVADTAAAKEAIEADMEVNGVYYGVILNAGITRDNTFVGLSDEEWFDVIDVNLNGF
YNVLRPALMPMIRARKPARIVTLSSVSGVIGNRGQVNYSASKAG"
aSModule        3274..3714
/domains="nrpspksdomains_HRGM_Genome_0011_CDS_01187_PKS_KR
.1"
/incomplete
/locus_tags="HRGM_Genome_0011_CDS_01187"
/tool="antismash"
/type="unknown"
CDS             3274..3978
/EC_number="1.1.1.100"
/NRPS_PKS="Domain: PKS_KR (0-147). E-value: 4.7e-18. Score:
57.5. Matches aSDomain:
nrpspksdomains_HRGM_Genome_0011_CDS_01187_PKS_KR.1"
/NRPS_PKS="type: other"
/codon_start=1
/gene="fabG_1"
/gene_functions="biosynthetic-additional (smcogs)
SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
187.6; E-value: 4.7e-57)"
/gene_kind="biosynthetic-additional"
/inference="ab initio prediction:Prodigal:002006"
/inference="similar to AA sequence:UniProtKB:P99093"
/locus_tag="HRGM_Genome_0011_CDS_01187"
/product="3-oxoacyl-[acyl-carrier-protein] reductase FabG"
/transl_table=11
/translation="MITGSSRGIGASIARHLANKYEVVLHARSKSDELLKMASELGAKF
LTFDVADTAAAKEAIEADMEVNGVYYGVILNAGITRDNTFVGLSDEEWFDVIDVNLNGF
YNVLRPALMPMIRARKPARIVTLSSVSGVIGNRGQVNYSASKAGIIGASKALAVELASR
GITVNCVAPGLIKTDMSEEILNSDFLDEVLKAIPAKRAGEASEVAGLVKFLLSDEASYI
TRQIIGVNGGLC"
CDS_motif       3277..3333
/aSTool="nrps_pks_domains"
/database="abmotifs"
/detection="hmmscan"
/domain_id="nrpspksmotif_HRGM_Genome_0011_CDS_01187_0001"
/evalue="8.80E-05"
/label="PKSI-KR_m1"
/locus_tag="HRGM_Genome_0011_CDS_01187"
/protein_end="20"
/protein_start="1"
/score="15.2"
/tool="antismash"
/translation="ITGSSRGIGASIARHLANKY"
CDS_motif       3646..3705
/aSTool="nrps_pks_domains"
/database="abmotifs"
/detection="hmmscan"
/domain_id="nrpspksmotif_HRGM_Genome_0011_CDS_01187_0002"
/evalue="1.00E-08"
/label="PKSI-KR_m4"
/locus_tag="HRGM_Genome_0011_CDS_01187"
/protein_end="144"
/protein_start="124"
/score="27.7"
/tool="antismash"
/translation="VTLSSVSGVIGNRGQVNYSAS"
CDS             3978..5231
/EC_number="2.3.1.179"
/NRPS_PKS="Domain: PKS_KS(Iterative-KS) (104-412). E-value:
3.2e-46. Score: 149.8. Matches aSDomain:
nrpspksdomains_HRGM_Genome_0011_CDS_01188_PKS_KS.1"
/NRPS_PKS="type: PKS/NRPS-like protein"
/codon_start=1
/gene="fabF_2"
/gene_functions="biosynthetic (rule-based-clusters)
arylpolyene: APE_KS1"
/gene_functions="biosynthetic-additional (smcogs)
SMCOG1022:Beta-ketoacyl synthase (Score: 301.4; E-value:
1.8e-91)"
/gene_kind="biosynthetic"
/inference="ab initio prediction:Prodigal:002006"
/inference="similar to AA sequence:UniProtKB:P73283"
/locus_tag="HRGM_Genome_0011_CDS_01188"
/product="3-oxoacyl-[acyl-carrier-protein] synthase 2"
/sec_met_domain="APE_KS1 (E-value: 1e-185, bitscore: 610.9,
seeds: 15, tool: rule-based-clusters)"
/transl_table=11
/translation="MRVFVTGIGAVSAFGNSWEEMRAKFLEGKNAVRYMSEWECYKDLN
TRLAAPIIDYKYPQEWDRKQLRSLGKVSCYSVHAAGLALKDAGLLKGDELNESNLDPSV
QDGRMGVASGSSTGSTDSILDMAKLVLDMDSGFNANTYIKMMPHTTAANIALFYSLKGR
IIPTSSACTSGSHAIGYAYESIKNGSIDMMLAGGAEELCVSEAYVFDKLYATSVKNSTP
NLSPTPFEKDRDGLVLGEGAGFLVLESEESALKRGAKIYAEVVGFGSTCDGTHITRPQS
ATMKAAMSIALRDANLEPKNIGYVNAHATATKHGDIAESIATNKLFGEDIAISSLKSYL
GHTLGACGGLEAIASIMMMREELFFPTINLSVIDPECAKLNYLKEPTPIKTDFVMSNNF
AFGGVNTSLIFKRVKNIF"
aSDomain        4290..5213
/ASF="found active site histidines: True"
/aSDomain="PKS_KS"
/aSTool="nrps_pks_domains"
/database="nrpspksdomains.hmm"
/detection="hmmscan"
/domain_id="nrpspksdomains_HRGM_Genome_0011_CDS_01188_PKS_
KS.1"
/evalue="3.20E-46"
/label="HRGM_Genome_0011_CDS_01188_PKS_KS.1"
/locus_tag="HRGM_Genome_0011_CDS_01188"
/protein_end="412"
/protein_start="104"
/score="149.8"
/tool="antismash"
/translation="QDGRMGVASGSSTGSTDSILDMAKLVLDMDSGFNANTYIKMMPHT
TAANIALFYSLKGRIIPTSSACTSGSHAIGYAYESIKNGSIDMMLAGGAEELCVSEAYV
FDKLYATSVKNSTPNLSPTPFEKDRDGLVLGEGAGFLVLESEESALKRGAKIYAEVVGF
GSTCDGTHITRPQSATMKAAMSIALRDANLEPKNIGYVNAHATATKHGDIAESIATNKL
FGEDIAISSLKSYLGHTLGACGGLEAIASIMMMREELFFPTINLSVIDPECAKLNYLKE
PTPIKTDFVMSNNFAFGGVNTSLIFKRV"
aSModule        4290..5213
/domains="nrpspksdomains_HRGM_Genome_0011_CDS_01188_PKS_KS
.1"
/incomplete
/iterative
/locus_tags="HRGM_Genome_0011_CDS_01188"
/tool="antismash"
/type="pks"
CDS             5243..5659
/codon_start=1
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01189"
/product="hypothetical protein"
/transl_table=11
/translation="MKKLVSLVAILAFATSLNARDDVKYHSLDFLNGPKAKNFLLPNVS
ISFGTGYSGQVIVKDLTSNKKTNGFNKSDEEACQIALLSALKTFQERALKEGGTKVVNL
TGYYKKQPFNSKTQFQCGSGALMSGVTLKGDIAK"
CDS             5659..6327
/codon_start=1
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01190"
/product="hypothetical protein"
/transl_table=11
/translation="MKFQVDFFDAIAYGDVGEDLARYKKEFDLAKIPPIQRRRLSSAAK
CAFSLLSGFDKLDMPVIFSSYEGEINRCFELETTLAKAEPVSPTSFSLSVHNAISSLLS
IEAKNHNEILAISSFSPVEDALQAAFLRLNDGYEKVLILAYHESIKQSYFDEKKPSFML
ALVVSKAKNERILTLKRAKKEKEICGNLLKSFIVNFDPKISKSWQSCSYPSSWDFSYEP
"
CDS             6317..7063
/codon_start=1
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01191"
/product="hypothetical protein"
/transl_table=11
/translation="MSLKILRTGSFFFFFAIICISGDLLLVPVVLLGLNKFKFVQNLCR
DLVRISWGFFIKVAKNCGRLDYKFELSELNGGSNLVIANHPSLLDVVFLVSKFKRINCI
VKGELGKNIFLFAAIRACNYIPNTNNEEFLQKSVEVLKGGENLLIFPEGTRTKDEIIFH
KAAAYIGVKGAKNIVCIGINMHPRSLRKNEPWYKISDEKIKYHFKEIKIFDVDMFLKDR
PSPVRARAMHDEISKIYKEEFGERAS"
CDS             7047..7304
/NRPS_PKS="Domain: PP-binding (7-80). E-value: 2e-10.
Score: 32.9. Matches aSDomain:
nrpspksdomains_HRGM_Genome_0011_CDS_01192_PP-binding.1"
/NRPS_PKS="type: other"
/codon_start=1
/gene_functions="biosynthetic-additional
(rule-based-clusters) PP-binding"
/gene_kind="biosynthetic-additional"
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01192"
/product="hypothetical protein"
/sec_met_domain="PP-binding (E-value: 7.9e-10, bitscore:
32.9, seeds: 164, tool: rule-based-clusters)"
/transl_table=11
/translation="MKELVNEIKELIITSLNLEDMKPSDIDENAPLFNDGLGLDSVDAL
ELGLAVQKKYGLVLDSKSSNLKEIFFSVSSLAKYIYENRK"
aSDomain        7068..7286
/aSDomain="PP-binding"
/aSTool="nrps_pks_domains"
/database="nrpspksdomains.hmm"
/detection="hmmscan"
/domain_id="nrpspksdomains_HRGM_Genome_0011_CDS_01192_PP-b
inding.1"
/evalue="2.00E-10"
/label="HRGM_Genome_0011_CDS_01192_PP-binding.1"
/locus_tag="HRGM_Genome_0011_CDS_01192"
/protein_end="80"
/protein_start="7"
/score="32.9"
/tool="antismash"
/translation="IKELIITSLNLEDMKPSDIDENAPLFNDGLGLDSVDALELGLAVQ
KKYGLVLDSKSSNLKEIFFSVSSLAKYIY"
aSModule        7068..7286
/domains="nrpspksdomains_HRGM_Genome_0011_CDS_01192_PP-bin
ding.1"
/incomplete
/locus_tags="HRGM_Genome_0011_CDS_01192"
/tool="antismash"
/type="unknown"
CDS             7307..7552
/NRPS_PKS="Domain: PP-binding (7-74). E-value: 2e-11.
Score: 36.1. Matches aSDomain:
nrpspksdomains_HRGM_Genome_0011_CDS_01193_PP-binding.1"
/NRPS_PKS="type: other"
/codon_start=1
/gene="acpP_1"
/gene_functions="biosynthetic-additional
(rule-based-clusters) PP-binding"
/gene_kind="biosynthetic-additional"
/inference="ab initio prediction:Prodigal:002006"
/inference="protein motif:HAMAP:MF_01217"
/locus_tag="HRGM_Genome_0011_CDS_01193"
/product="Acyl carrier protein"
/sec_met_domain="PP-binding (E-value: 8.1e-11, bitscore:
36.1, seeds: 164, tool: rule-based-clusters)"
/transl_table=11
/translation="MSEKEIFEILKKALIDLFEIDESKIKPETRIYEDLQIDSIDAIDM
IDYIKRQTGHRLMPEDFKNVKTLDNIVKAVAKKFEA"
aSDomain        7328..7528
/aSDomain="PP-binding"
/aSTool="nrps_pks_domains"
/database="nrpspksdomains.hmm"
/detection="hmmscan"
/domain_id="nrpspksdomains_HRGM_Genome_0011_CDS_01193_PP-b
inding.1"
/evalue="2.00E-11"
/label="HRGM_Genome_0011_CDS_01193_PP-binding.1"
/locus_tag="HRGM_Genome_0011_CDS_01193"
/protein_end="74"
/protein_start="7"
/score="36.1"
/tool="antismash"
/translation="EILKKALIDLFEIDESKIKPETRIYEDLQIDSIDAIDMIDYIKRQ
TGHRLMPEDFKNVKTLDNIVKAV"
aSModule        7328..7528
/domains="nrpspksdomains_HRGM_Genome_0011_CDS_01193_PP-bin
ding.1"
/incomplete
/locus_tags="HRGM_Genome_0011_CDS_01193"
/tool="antismash"
/type="unknown"
CDS             7542..8087
/codon_start=1
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01194"
/product="hypothetical protein"
/transl_table=11
/translation="MKHKIVNLALVLVSIAYPLVLFFWQENATLIFGVLCVLWGLRAYF
ESGKKRQVCLAAGIFFAICAIFRSVNLALLYPSIVSLGFLAIFFYSLKGEAVITKIARL
KEKNIDEKVVSYTRGLTKIWCLFFVFNAVLVFVLSCFENKFYWSIYCSFISYILMGFLF
FGEILYRKVFILKRKNGV"
CDS             8077..9633
/NRPS_PKS="Domain: AMP-binding (99-250). E-value: 3.9e-17.
Score: 53.6. Matches aSDomain:
nrpspksdomains_HRGM_Genome_0011_CDS_01195_AMP-binding.1"
/NRPS_PKS="type: NRPS-like protein"
/codon_start=1
/gene_functions="biosynthetic-additional
(rule-based-clusters) AMP-binding"
/gene_functions="biosynthetic-additional (smcogs)
SMCOG1002:AMP-dependent synthetase and ligase (Score: 44;
E-value: 1.8e-13)"
/gene_kind="biosynthetic-additional"
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01195"
/product="hypothetical protein"
/sec_met_domain="AMP-binding (E-value: 1.2e-12, bitscore:
40.8, seeds: 400, tool: rule-based-clusters)"
/transl_table=11
/translation="MEFENSLKEFKFVDIDKNLYSQVGIFGANLKEYGVSEIEIYLSET
FDFCVAFFGSLAIGVKPILLAKPIFSSDKFNINDENFKNFLTPARNMEPKFNLNSTFFL
QTSGSTGNSKNIPKRLGAMIEEGLFLKEELGVNESDTFFSSVSHQHMFGLTFKVFLPII
SGAKVVSRELNYPEAIFELELENLSFITSPVLLQTLISSPRAAEILGLKNIICAGSALK
SELRASIAKLSSACIIDIYGSTETGVVARNLGDELLLFSKVKADLSEDEALNVSSPWCE
FFQTSDWAQINGNRLTLKGRIDRIVKLNDKRVNLISIENKMLESGLLKDCYCDTHPKFK
RLAALLELSEEGVKLFRDSGKKGVVARLNELLRPEFKNSVRYFKIVSSLCKNAQGKFIK
ANFKELLEKIGEPSWDKSSENGIYKFKTKLSPALGIFTEHFPNLPLLPGFVQLDFVFKF
ARELGAEIGDQCVVENLKFLKFVRPNDELRIEISQKDEKVYFEIFCNGARSAAGRIKLG
L"
aSDomain        8374..8826
/aSDomain="AMP-binding"
/aSTool="nrps_pks_domains"
/database="nrpspksdomains.hmm"
/detection="hmmscan"
/domain_id="nrpspksdomains_HRGM_Genome_0011_CDS_01195_AMP-
binding.1"
/evalue="3.90E-17"
/label="HRGM_Genome_0011_CDS_01195_AMP-binding.1"
/locus_tag="HRGM_Genome_0011_CDS_01195"
/protein_end="250"
/protein_start="99"
/score="53.6"
/specificity="consensus: X"
/tool="antismash"
/translation="STFFLQTSGSTGNSKNIPKRLGAMIEEGLFLKEELGVNESDTFFS
SVSHQHMFGLTFKVFLPIISGAKVVSRELNYPEAIFELELENLSFITSPVLLQTLISSP
RAAEILGLKNIICAGSALKSELRASIAKLSSACIIDIYGSTETGVVAR"
aSModule        8374..8826
/domains="nrpspksdomains_HRGM_Genome_0011_CDS_01195_AMP-bi
nding.1"
/incomplete
/locus_tags="HRGM_Genome_0011_CDS_01195"
/starter_module
/tool="antismash"
/type="nrps"
CDS             9630..11240
/codon_start=1
/gene_functions="biosynthetic-additional
(rule-based-clusters) Glycos_transf_2"
/gene_functions="biosynthetic-additional (smcogs)
SMCOG1123:polyprenol-monophosphomannose synthase ppm1
(Score: 60.1; E-value: 4.3e-18)"
/gene_kind="biosynthetic-additional"
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01196"
/note="smCOG tree PNG image:
smcogs/HRGM_Genome_0011_CDS_01196.png"
/product="hypothetical protein"
/sec_met_domain="Glycos_transf_2 (E-value: 9.3e-20,
bitscore: 64.9, seeds: 256, tool: rule-based-clusters)"
/transl_table=11
/translation="MKTLFLIPFYNHPEKIKALCEALASYDLPILIVDDGSNETSKKAL
QNLSEFGVEIFTRAQNGGKGAALKDGFRHAVQNGYTHAFQIDADFQHDISEVTEFLELS
RKYPYDMIMADPIYGEDAPKSRFYGRKITNFWVKVNTLSTNIKDAMCGFRIYPLKELES
ATFQSSSNRMEFDMEILVNAVRAGIRLKWIPLKVRYEKGGISHFKMLEDNVLISLMHAK
YFFSLVPFLLGKAFKGQKYVWWQKGERSNEFFLRVSLFLTKNLPIFLIKPIVMIVVCFY
YIFSKIERKNIREFLQNVEKFSGKKPTTGVFRNFYEFGIAICDKFRIWQNGVLENELDI
DELMWIKEEFEASKRGRILLTSHLGNVEICKTLSLRSPSFRMIILVYSKGNENFYKILE
QISKGQIKLISVENLDAAAMLDLKEAVEGGVNIGIMGDRTPVNGDKFVEVSFLGKMAKF
NYGPYLLAGILGVKMSTLWCVKNGDKFSIELSDIADEIKLGRDRKASVMPYVQSYVRQL
EDHACKNPSQWFNFFDFWR"
CDS             11243..11665
/EC_number="3.1.2.-"
/codon_start=1
/db_xref="COG:COG0824"
/gene="ybgC_2"
/inference="ab initio prediction:Prodigal:002006"
/inference="similar to AA sequence:UniProtKB:P0A8Z3"
/locus_tag="HRGM_Genome_0011_CDS_01197"
/product="Acyl-CoA thioester hydrolase YbgC"
/transl_table=11
/translation="MKISHVSTFKVAFFDVDSMEVMWHGNYVKYLEMARCELLDKLGYN
YIAMKKDGYAFPIVKLDVKYVRPAFFNDFIKVTTTLSECETFLKFHYLIENEKGEKLSE
ANTAQAVIDMKSLQTCFEMPESLKKAIEAYTKKENL"
CDS             11662..12180
/codon_start=1
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01198"
/product="hypothetical protein"
/transl_table=11
/translation="MKKITLFLAIFISCFGYELSELKNIVKTDGVGGNFTQTKSLAGFN
KSIKSTGEFRLEKDGLYWDTLEPVVSKVFINKDGIFKNENGKLEKTTANFDEKLFLAII
SLDESELRKEFDIKTSGSLKEWEIELSPKNLLFKQIFKSIKISGDDVVKKIELDEVSGD
KTINEFSLK"
CDS             12177..14405
/codon_start=1
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01199"
/product="hypothetical protein"
/transl_table=11
/translation="MKKLVTILAFIFVFLASLGYSLASLKNVQTDIFSLINFKDAKEAK
VLKEVQDEMASNFLVLVNSKELAKNVQSLAFKSSLFKSFEANIDVNLNDIKNDINRSKI
ALLSRADLELLKSDKNAFFKKRAEEIFNSFSFMLLNVKDDFFSLSSGFSAKNGNVSLNL
ADLMLEVKDRERSFFLLKGELKSGVGGEGLIKFYNELNALKVGQNELFVHSSALYQAFS
KQKNESESLYMSVVSLSLTAIFLMLAFRNLRIFYVIFIAAFGFSLAFAGTLLCLGELNI
LTILISTSLIGLMFDYVLHWLSKNEGEAIRTDSIKNMLKIFLLGLFITLSGYLAFTFSD
LRLLKEVALFSAFALVAAFLASYFFIPLVFEGVKFYRSKLFDRFLTKFCKLSALVARHL
GVKFLAFSLILLAIFIGLDLKNLSKSENVKDYSNMPKSLLANSSYILSLTGNNQNTMIV
TRSGGDILGDEKSLLDELKKRNLIKDESSLSDMFLSKSEQGELKEVFKKVLDDEQIYAV
YEKFGFNKDEIRDEILKILGEKELGVSEILALKSMKDFKKFMLDENASVAYASGFVKGA
ASDDVLERYNAFSLNFASSLNESLTQAKELALKLKIAALVIAFLLLWFYFSALISALVM
GTIVFGVLLTLFIFAVFGINLSIFGVFGLILASAVGIDYMIFALNESLSEKERIYGIFC
AFITSFISFFTLSFSQTAALSVFGLSVSLCVLIYGLCASVLACKNIKI"
CDS             complement(14456..15706)
/EC_number="4.2.2.2"
/codon_start=1
/db_xref="COG:COG3866"
/gene="pel"
/inference="ab initio prediction:Prodigal:002006"
/inference="similar to AA sequence:UniProtKB:P39116"
/locus_tag="HRGM_Genome_0011_CDS_01200"
/product="Pectate lyase"
/transl_table=11
/translation="MFKKILFLAVSSLFAFGAEAQVGEIKASDLPFGYASIGAEQNFGG
YAGKESKEVVVKDRQELVKYAQMGGYVIYVDGLIDLSEGKIPQNGNSLGLDKFMSEISG
GEFDTYTKFMQAYGASCHANLDGSQDPKLAALRKNLANEYKKLIVVPVASNTTIIGLGE
NSGIKGGSLLLKNVQNIAIRNMLVEDAFDPFPDIQKNDGFNAQYDGISIESSKNIWIDH
CHFKDTVDLSHVHLAGGELTKWQTYDGLCDIKGDSAAITISHNIFENHDKTMLIGSRDS
DGSSETRTITVAHNIFDNCAQRLPMARNAKVHVYNNFYDSKDGFYDQKYAIGVRFGSLV
YAQNNYFTNGVKISYKCNKGTIFESGNIDLSKKGSVCEKLDKPPFEPPYKFELLEASNV
QKEVNQNAGTGKLAVIK"
CDS             complement(15829..16926)
/codon_start=1
/gene="cinA"
/inference="ab initio prediction:Prodigal:002006"
/inference="protein motif:HAMAP:MF_00226_B"
/locus_tag="HRGM_Genome_0011_CDS_01201"
/product="Putative competence-damage inducible protein"
/transl_table=11
/translation="MRQSILIIGEDLEINREFLNYIFQSYEDHFGELGVVSFAPKNSKE
LPFIIENLSKNYDFVSIFGSDENFAIAAKIVATLTGGSLELKDSTTLALKDSLDYSKNS
FLASLNNAQINLIKANPNEELGEFLTDYEPDFSYFHLIDIDADSAKILMLPLAKTYEVD
ITLAQILPNLILVRAKSNKFGQIESFLQGVKTLFSQKFIPQKDVIKFVAKKLMQNGLKI
SFAESCTAGLVAAKFARYGGISASFDGSLVTYANHIKHEWLGVEDEILDTYGAVSEPCV
KAMVKGTLSTTNADFALAISGIAGPGGGTASKPVGTVYVAAGDRNGNIEVERLLLKGER
NYVREQSVLSAYLCLLRLKSEIFFA"
CDS             17022..19778
/EC_number="6.1.1.5"
/codon_start=1
/db_xref="COG:COG0060"
/gene="ileS"
/inference="ab initio prediction:Prodigal:002006"
/inference="similar to AA sequence:UniProtKB:P00956"
/locus_tag="HRGM_Genome_0011_CDS_01202"
/product="Isoleucine--tRNA ligase"
/transl_table=11
/translation="MDYKETLLLPETNFPMRGNLPQNEPQRLKSWYEERKVYEKMKKNR
QNAVKNFNIHDGPPYANGHLHIGHALNKILKDIITKTHYFYGENVRYVPGWDCHGLPIE
QQVEVKLGDKKKDLSKVEIRELCRQHAREFIDIQRNEFKSLGIIGDFENPYMTMKFEFE
ADIYKALCEIAKKGLLVERSKPVYWSWAARSALAEAEVEYEEKEDYSIYVAFELDSDAL
EKLGVKEASAVIWTTTPWTLPANQAISLKPDEIYVLTAENLIFAKPLLESVVQSGLSKG
EIKKEFKSSLLENTHAINPLNGRKSRFLLGDHVMMDGGTGLVHTAPGHGEDDYYVCLKY
GFSEILMPVDDGGCYDESLKHHGLFRSDVVDEFVGMHIFKANEKILELLGKSLLSVSKF
RHSYPFCWRTHKPVIYRATKQWFIAMDEAKLGGKTLRQTAREELEKVKFYPSVGIKRIG
SMIENRPDWCISRQRDWGVPIAFFRDKATKEVIFDSEILDHIVAIFKEKGADAWWALSI
DELLPKGTKYKAENLEKVMDILDVWFDSGSTWHAVLQSDNYDAGKYPASMYLEGSDQHR
GWFQSSLLVSTAINSHAPYESILTHGFTVDAKGEKMSKSKGNVIAPQDVAKTHGVEILR
LWVGMSDYSSDLKISEDILKQISEQYRKIRNTIRFLLANVNDLESLNTEFNILDKWILA
RAKKVFDEASSCFRNYDFSKGFNILLNFLSADLSGVYLDVCKDRLYCDAKDAPRRRSAQ
SAMAIITKALLPLIAPTLTYTVDEVMDYAPKIIKGEAKDAFDLVYEPIKFDLSFEDELL
FASREKFNEIVDVLKKDKKIKSTLELSLETTNHNITGYDEREVADLYMVSSVKAYDDSE
PLAEFELEGDKFKIIASNLHKCPRCWKFNASKEDALCPRCEEVISAK"
CDS             19878..21236
/EC_number="6.3.5.7"
/codon_start=1
/db_xref="COG:COG0154"
/gene="gatA"
/gene_functions="biosynthetic-additional (smcogs)
SMCOG1105:amidase (Score: 393.8; E-value: 1.9e-119)"
/gene_kind="biosynthetic-additional"
/inference="ab initio prediction:Prodigal:002006"
/inference="similar to AA sequence:UniProtKB:O66610"
/locus_tag="HRGM_Genome_0011_CDS_01203"
/note="smCOG tree PNG image:
smcogs/HRGM_Genome_0011_CDS_01203.png"
/product="Glutamyl-tRNA(Gln) amidotransferase subunit A"
/transl_table=11
/translation="MVTLKEALKFSAEEIKNLRAELEAKIIKEKELGAYVEQLANLEIA
KLGEGVPIAIKDNIQVKGWSVTCASKILQGYVAPYNATVIEKLLSKNLAPFGRTNMDEF
AMGSTTESSFYGKTLNPLNHAHVPGGSSGGSAAAVAAGLAVAALGSDTGGSIRQPAAFC
GCVGFKPTYGRVSRYGLGAYSSSLDQIGPIAQNVEDAAILYDAIAGHDPKDSTSADVPF
ESISDKIDSEKKLKICVIKNYVENASEQTKAALNLAIEKLKSHGHSVTYTNFEDSKYDV
ATYYIIATAEASANLSRYDGVRYGRRADARNLKELYVNSRSEGFGEEVKRRILLGTFVL
SSGYYDAYYIKAQKARAHIKAQYERILEENDLIFMPVAPSTAYKFGAHSDPLQAYLSDI
YTISVNLAGLPAISVPVGKDDQNLNVSAQLIAKAWDEQTLINGAKSLENLIKG"
CDS             21241..22689
/EC_number="1.1.1.205"
/codon_start=1
/gene="guaB"
/inference="ab initio prediction:Prodigal:002006"
/inference="similar to AA sequence:UniProtKB:P99106"
/locus_tag="HRGM_Genome_0011_CDS_01204"
/product="Inosine-5'-monophosphate dehydrogenase"
/transl_table=11
/translation="MKIVKRALTFEDVLLVPQYSEILPKQVDVKTRISKNVTLNIPIVS
AAMDTVTEHRTAIMMARLGGIGVIHKNMDIESQAKEVKRVKKSESGVIIDPIFINPEAT
VAEALSLMSDLHISGVPVIDKDRKLIGILTNRDLRFETNMSTLVKDRMTKAPLITAPKG
CTLDDAEKIFSQNRVEKLPIVDKDGRLDGLITIKDLKKRKEYPNANKDSYGRLRVAAAI
GVGQIERAKALVDAGVDVIVIDSAHGHSKGIIDTLKEVKANFNVDVIAGNIANPAAVKD
LVEAGADGIKVGIGPGSICTTRIVAGVGVPQISAIDDCASEAAKYGIPVIADGGLKYSG
DVAKALAAGAACVMAGSLLAGCEESPGELITFQGRQYKVYRGMGSIGAMTKGSSDRYFQ
EGTAQDKLVPEGIEGRVPFAGSIKDVIHQLIGGLRSAMGYVGAKDIPTLQERAEFVEIT
SAGLKESHVHDVVITHEAPNYKVN"
CDS             22689..23795
/EC_number="2.3.1.31"
/codon_start=1
/db_xref="COG:COG2021"
/gene="metXA"
/gene_functions="biosynthetic-additional
(rule-based-clusters) PF00561"
/gene_kind="biosynthetic-additional"
/inference="ab initio prediction:Prodigal:002006"
/inference="similar to AA sequence:UniProtKB:E0UR96"
/locus_tag="HRGM_Genome_0011_CDS_01205"
/product="Homoserine O-acetyltransferase"
/sec_met_domain="PF00561 (E-value: 1.1e-22, bitscore: 74.6,
seeds: 48, tool: rule-based-clusters)"
/transl_table=11
/translation="MLDLQTRTIKFNEPLYLESGRILSNFKLIYETYGTLNADKSNVII
ICHALTGSHHAAGTYTGDEKAGWWDGLIGSKKAVDTDKFYVICVNILGSCFGSTSPLSV
DRSSGKEYRLNFPVLAISDVVKAQMRLFNELGITRARAVIGGSLGGMQALCYAIEFPEF
AQDIIMLASTYQTKPWAIAFNKIAIEAILNDENFKNGEYDVEFIRKNGLKGMAYGRMAG
HISFLSPDSMDEKFGRNYVETDGLYELSGRFQVDRYMEYNGYNFPKRFDPLSYLYIVKM
MNIFDCTRHYDNLKDALVPIKANLHLIAFKGDLLFPPCCMREIYDTLCEMGRGENTNFV
EIDSNYGHDAFLVEIEKFDGYIKNILKG"
CDS             23799..23990
/EC_number="3.1.11.6"
/codon_start=1
/gene="xseB"
/inference="ab initio prediction:Prodigal:002006"
/inference="protein motif:HAMAP:MF_00337"
/locus_tag="HRGM_Genome_0011_CDS_01206"
/product="Exodeoxyribonuclease 7 small subunit"
/transl_table=11
/translation="MEQKEQSFEEKLALADKILNDLNKDDVSLENSIKLHEQGKKLLNE
AREILENAKLSIKQVDDE"
CDS             23983..24777
/codon_start=1
/gene_functions="biosynthetic-additional (smcogs)
SMCOG1294:Nitrilase/cyanide hydratase and apolipoprotein
(Score: 102; E-value: 6e-31)"
/gene_kind="biosynthetic-additional"
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01207"
/note="smCOG tree PNG image:
smcogs/HRGM_Genome_0011_CDS_01207.png"
/product="hypothetical protein"
/transl_table=11
/translation="MSRICALQLPTQPLSEARLDYYLKICADENARLVVLGEYVLNSFF
KELISMPKSLIKEQSERKKEALFAMAKKYDLNIVAPIVNLKGKEIFKSLAKFTPTQVKL
YDQQILMPYAHWNEAKFFNNTSDELNLPIFTYDKFKVGVMFGYEAHFDVCWAYMSAKKV
DIVLVPTACTFFSQARWEELLKVRAFTNNVYVLRVNRVGSHKSEDAQWSFYGDSMLINP
FGEVKNRLGKNEEMMIDELSKKELSEARSTWGFMQIEAKFKR"
CDS             24852..25205
/codon_start=1
/gene_functions="other (smcogs) SMCOG1198:hypothetical
protein (Score: 73.3; E-value: 3e-22)"
/gene_kind="other"
/inference="ab initio prediction:Prodigal:002006"
/locus_tag="HRGM_Genome_0011_CDS_01208"
/note="smCOG tree PNG image:
smcogs/HRGM_Genome_0011_CDS_01208.png"
/product="hypothetical protein"
/transl_table=11
/translation="MKRSEIEKYIKEKFDILGEQLFPKYPNFSAFRHKKNKKWFALLMQ
LSASKLGLKSDEMIEVLNLKCSPDLAMVLVDERQIFKAYHMNKKHWISVNLNSKISQKT
VFDLIDESFSLSK"
ORIGIN
1 ggtggggcaa gtggcagttg gtaaattctt atcaaagatt agtttgaaaa actcaaatcc
61 tttaaaatat aaaaaactta ggagcaaaga tgctagctgg cgagctactt aaaagccatt
121 ttgctaaatt tgatctagtg gcagtgctta gtaaattttt agagcaaagt cattttgata
181 aagaaaaatt tggcctactt aaacaaaata actttaaaat tctagataaa aatataaagc
241 aagagatagt tgggactgct ggttttaaag agttttttga tgagaaattt aggggctttt
301 tatgcgagct tatgcaaagt agagttttaa ttgtttctgg caaagagtat aaatttagcg
361 agcttgaaat ttatacttgt tttgacgcaa atacttataa acggcagtgt gaggcaggag
421 agatttactt tcataacttt ggttttgaca tatcttttaa aagtgatcta tcactttatg
481 gtggcgtttt agtaagaagc ctaaagccct taaacgggca aaattttatc tttgggccaa
541 gaaaatgtgc cttgcatatc ttaaatagca aaatgagcaa tttaaacttt gatctaaaag
601 aggctgattt tagaaaagat gggattactt ttacgccacg tattagatca tttggcgatg
661 aaaaccagca aaaaaatgat tgtcttagag catttactgc cgagtttgaa aaagcattag
721 agtttgatga aaattataaa aagagattaa atgcctataa aaaggggtga aattcatctt
781 tctatcagct tttgcggtga gaaatttagc ccaaaaatgc tagataaaaa agatcgtaga
841 aagcttaaaa aatacccaaa tttaataaaa caaaactcat ttaaaatatc tcgctactta
901 aaatttaaag caaagatgcg aggcaaaatc tgtctttctc ataaagaaaa tatcgcagtt
961 ttagtcattt caaaagaaaa gatcggagtc gatgtagaag agctaaagca gagaaatttt
1021 gacgctatag ctagcttttg ctttacaaaa gaagagagca aaattttggc aaatgcaaaa
1081 gataaaacgc aaaaatttta tgaaatttat actgcaaaag aggcaatttt aaagcttaaa
1141 aatttatcgt ttagcgatct tggtactacc aactacgatg aaatggcaaa aagatactta
1201 attattaata attcatttat tatttgcctt gcatttaagc aatgcaaaga tataattatt
1261 aaacttttgt aatttttaac attaaaaggt aaagattgct tataaaaaaa atagtcataa
1321 tccttgctat ttcgcttttt gctcttggat gtgcaaagaa atttgatacg ccacagatgg
1381 tagattttga cttgaaaaca tttaaggtaa gctcatcaaa aggtctactt ttgctttacg
1441 tgcaaaatag caagaatgag tataaattta gccttgtaaa tgcacttggc gcgccagaag
1501 ctaggcgact tttaaaagat ggcagcttta aaaatttagg ttttttgccg ccaaatagtg
1561 cctataatga actttttata aaagtactag agatgataaa agatgaaaaa agcgagcaaa
1621 aatttatgat agatgatcaa tattatgagg tagaaagtgt tgatctacgt tagcaaacca
1681 gccattatca gtgccgcagg gagcagctgt gatgagaatt taagctcgct tttaagcgga
1741 aagaggtttc tgagccttag cagtgagttt catcctgaga ataaattttt agttgcgaaa
1801 tttgataaag cactgccaga gtttgccaag aagacaaaag aacactttaa aacaagaacc
1861 aatgccttgc ttttaaacac gcttcttgag cttgatgatg agatcaagag ggctatcaaa
1921 aaatttggca aaagccgtgt aggtgttatt ttaggcacta caacgagtgg aattgaagaa
1981 aatttttgga cttttaaaga gtatataaaa actgaaattt ttgataaaag caagtttggt
2041 atagatagaa actgtcttgc aaatgtgacc gaatttgtga ccgaatttta tggattagaa
2101 ggtccaagtt tttgtgtttc aactgcctgt acttctggtg ttaaggcgat tattgaggca
2161 caaagactaa taaaaagcga tatttgcgat gcggttatat gcggcggcgt cgatagttta
2221 aacacattaa ccataaatgg ctttaactca cttagcattt taagtcaaaa accaagccag
2281 ccattttcta aaaacagaga gggcataaac ataggcgagg gggctgggct gtttttgctt
2341 agccgtgatc aaatttcaga cgttatcgtc gctggttcag cctcaaactg cgacgctttt
2401 catatgactc aacctgattt tagtgccaaa atggcaattt gttgtataga agaagcttta
2461 aaaaaagctg acatgagagg cgtagactat gtaaatttgc atggtaccgg cacgcaagca
2521 aatgacaaaa tggaggcaaa agctgtaaat ttaacgcttg gctttgcata tgctagctcg
2581 ttaaagccac agatcggaca cacgctagga gctgctggag caatagaaag cgccatttgc
2641 tccatgcttt gcatggagga aaatagcacc ttgccaccac acgtttatga cggagcatat
2701 gacgagagtt tggaagctat aaatttagta aaaagcggca cgaaatttga cgtaaaaacg
2761 gcgatgtcgc tatcttttgc ctttggcgga gataacgccg cgataatttt taaaagagtg
2821 agatgatgat aagtgattat ttgccgcaca gtagcgccat aactctgatc gatgaaattt
2881 tagaatttac cccttgcgag agcataaaag taagaagtgt gataaatgag caaactccat
2941 ttttggaaga tgggaaattt tacatgcaaa aagcgattga gatgatggct caaagccttg
3001 gtgtttatga ctcaaagatg cgtgagttaa ggggcgaaaa ggcgatattt ggctttttgc
3061 ttggcagtag gaaatttgaa atttttaggc cgtattttaa agtaggtgat gagatagtga
3121 tcgtctcaaa gtgctcgatc caagatgaga gtggatttgg cgtttatgac agcgagcttt
3181 ttgtaaatgg agagcttggc gcaaggacgg ttttaaacgt gatgagccct gatgaagaat
3241 ttgtaaaaaa ggcacttagt gagtaagaga gtattgataa ctggatcaag tagaggcata
3301 ggagctagca tagctaggca ccttgctaac aagtacgaag tggtgcttca cgcaagaagt
3361 aagagcgatg agcttttaaa gatggctagt gaacttgggg ctaaattttt gacatttgac
3421 gtggctgata ctgctgctgc taaagaggcc atagaggctg acatggaggt aaatggcgtt
3481 tattacggtg ttattttaaa cgctggcata acaagagata acacctttgt ggggctgagt
3541 gacgaagagt ggtttgacgt gatagatgta aatttaaatg gcttttacaa cgtgctaaga
3601 ccagcgctaa tgcccatgat aagggctaga aagccagcta gaatagtaac actaagctct
3661 gtttcggggg ttatcggcaa tagaggtcag gtgaactact cagctagcaa ggcaggcatc
3721 ataggagcta gcaaagccct tgcagtagag cttgcaagta gaggcataac agtaaactgc
3781 gtagcgcccg ggcttataaa gacagatatg agcgaggaaa ttttaaatag cgacttttta
3841 gatgaggtgc taaaggccat acctgcaaaa agagctggcg aggctagcga ggtggcaggg
3901 ctggttaaat ttctactaag cgacgaggct agctacatca caaggcagat tatcggcgta
3961 aatggaggac tttgctaatg cgtgtatttg tcacaggtat cggcgcagtc agtgcttttg
4021 gcaacagctg ggaggagatg agggctaaat ttcttgaggg taaaaacgct gttagataca
4081 tgagcgagtg ggagtgctat aaggacctaa acacgcgcct agctgcacca attatagact
4141 acaaatatcc gcaagagtgg gatagaaaac agctaagaag ccttggcaag gtgtcgtgtt
4201 acagtgtgca tgcggctgga cttgctttaa aagatgctgg attattaaaa ggtgatgagt
4261 taaatgagtc aaatttagac ccaagtgtgc aagatggcag aatgggtgtg gcaagcggct
4321 caagtactgg cagtaccgac tctatccttg atatggcaaa gctagttttg gacatggata
4381 gcggttttaa cgcaaatacc tatataaaga tgatgcctca caccacagcg gcaaatatcg
4441 cgctatttta ctcgctaaaa ggacgtataa tcccgacgtc atcggcctgc acgagcggtt
4501 cgcatgccat tggctacgca tacgagagca taaaaaatgg cagcatagat atgatgctag
4561 ctggaggggc tgaagagctt tgcgtgagcg aggcatacgt ttttgacaag ctttacgcga
4621 ctagtgtaaa aaatagcacg ccaaatttga gtccaacgcc atttgaaaaa gatagagatg
4681 gcttggtact tggcgaggga gctggatttt tagtgcttga aagtgaagag agtgcattaa
4741 aaagaggagc taaaatttac gctgaggtcg ttggttttgg ctcaacgtgt gatggcacac
4801 acatcacaag accacaaagc gctacgatga aagcggctat gagcatagcg cttcgtgacg
4861 caaatttaga gccaaaaaac ataggctacg taaatgctca tgcgactgca acaaagcatg
4921 gcgacatagc cgagagtata gctacaaaca agctttttgg agaggatatt gccattagct
4981 cgcttaaaag ttatcttggt catacgcttg gtgcttgtgg aggactggag gcgatcgcct
5041 ctataatgat gatgagagaa gagctatttt tcccaactat aaatttaagt gtgatcgatc
5101 ccgagtgtgc aaagctaaac tatttaaaag agccaactcc gataaaaacg gactttgtta
5161 tgagtaataa ctttgcattt ggtggtgtaa atacatcttt gatatttaaa agagttaaaa
5221 acatttttta aaaaggataa acatgaaaaa attagtttca ttagttgcca ttttggcatt
5281 tgctacaagt cttaatgcaa gagatgatgt gaaatatcac tcacttgatt tcctaaatgg
5341 cccaaaagct aaaaatttct tacttccaaa tgtaagtatc agctttggca caggctatag
5401 cggtcaggta attgtaaaag acctgacatc aaataaaaag acaaatggtt ttaataaaag
5461 tgatgaagag gcatgccaaa tcgcacttct ttcggcctta aagactttcc aagaaagagc
5521 attaaaagaa ggcggcacta aggttgtaaa tttaactggc tactacaaaa aacagccatt
5581 taactcaaaa actcagtttc agtgcggaag cggtgctttg atgtctggtg ttactctaaa
5641 aggtgatatc gcgaaataat gaaatttcaa gttgattttt ttgacgcgat agcttatggc
5701 gatgtcggcg aggatctggc tagatacaaa aaagaatttg atctagcaaa aattccacca
5761 attcaaagaa gaaggctaag tagtgctgca aagtgcgctt ttagcctact tagtggcttt
5821 gataagcttg atatgccagt tatttttagc tcgtatgaag gagagataaa tcgctgcttt
5881 gagctagaga ctacactggc aaaagctgag ccagtttcgc ctacttcgtt ttcactttct
5941 gtgcataacg ctatctcgtc gcttcttagt atagaagcta aaaatcacaa tgaaattctt
6001 gccatttcat catttagccc agtcgaagat gcgctgcaag cggcattttt aagactaaat
6061 gacggatatg aaaaggtgct aatacttgcc tatcacgagt cgataaagca gagttatttt
6121 gatgagaaaa agccgtcatt tatgctcgct cttgttgtct caaaggcaaa aaatgagagg
6181 attttaactc taaaaagagc caaaaaagaa aaagaaattt gcgggaattt attaaaaagc
6241 tttattgtaa attttgatcc aaaaatatct aaaagctggc aaagttgtag ttatccttca
6301 tcttgggatt ttagctatga gccttaaaat tttaagaact ggatctttct ttttcttttt
6361 tgcgatcatt tgcataagcg gagatttgct acttgtgcca gtagtacttt tggggctaaa
6421 taaatttaaa tttgtacaaa atttatgccg tgatctagtt agaatttctt ggggattttt
6481 tataaaagtt gctaaaaatt gtgggcgttt ggactataaa tttgagctta gcgagctaaa
6541 tggcggatca aatttggtca tagcaaatca cccttcgctt cttgatgtgg tctttttggt
6601 ttcaaaattt aaaaggataa actgtatcgt aaagggcgag cttggcaaaa atatattttt
6661 atttgcagct attagggctt gcaactacat accaaacaca aataacgagg aatttttaca
6721 aaaaagcgta gaggttttaa aaggtggtga aaatttattg attttcccag agggcacacg
6781 tacgaaagat gaaattattt ttcataaggc agcagcttac ataggtgtaa aaggcgctaa
6841 aaatattgtt tgcatcggta tcaatatgca cccaagaagc cttagaaaaa atgaaccatg
6901 gtacaaaata tcagatgaaa agataaaata tcattttaaa gagataaaaa tttttgatgt
6961 tgatatgttt ttaaaggata ggccaagccc cgtgagggcc agggcaatgc atgatgagat
7021 aagtaaaatt tataaggagg aatttggtga aagagctagt taatgagata aaagagttga
7081 tcatcacaag cttaaattta gaggatatga agccaagcga tattgatgag aatgcgccac
7141 tttttaatga tggtcttgga cttgatagcg ttgatgcctt agagcttggg cttgcggtgc
7201 agaaaaaata tggcctcgtg cttgactcaa agagctcaaa tctaaaagag atatttttta
7261 gtgtatcttc tcttgcaaaa tacatttacg aaaataggaa ataactatga gtgaaaaaga
7321 aatttttgaa attttaaaga aagccttgat cgatcttttt gagatagatg agagcaagat
7381 aaagccagaa actaggatat atgaggattt gcagatcgat agcatcgacg ctattgatat
7441 gattgattac atcaaacgtc aaaccggaca taggctgatg ccagaggatt ttaaaaacgt
7501 aaaaacgctt gataatattg taaaagccgt agcaaagaaa tttgaagcat aaaatagtaa
7561 acctagcact agttttagta agcattgctt atcctttagt gctatttttt tggcaagaaa
7621 acgccacttt gatatttggt gttttgtgtg tgctttgggg gcttagagcc tattttgaaa
7681 gtggtaagaa aagacaggtt tgcttagcgg ctgggatatt ttttgccatt tgcgctattt
7741 ttagaagcgt aaatctagca cttttatatc caagtatcgt aagccttggc tttttggcga
7801 tcttttttta cagcttaaag ggcgaggctg ttataacaaa aatcgctaga ttaaaagaga
7861 aaaatataga tgaaaaggtc gttagctaca caagagggct aacaaaaatt tggtgcttat
7921 tttttgtatt taatgcggtt ttagtatttg ttttatcgtg ctttgaaaat aaattttatt
7981 ggagcattta ctgctccttt atctcttata ttttgatggg atttttgttt tttggagaaa
8041 ttttatatcg taaagttttt attttaaaga ggaaaaatgg agtttgaaaa tagtctaaaa
8101 gagtttaaat ttgttgatat tgataaaaat ttatactcac aagttggtat ttttggggca
8161 aatttaaaag agtatggtgt gagtgagata gagatctatc taagtgaaac ttttgacttt
8221 tgtgtagcct tttttggatc acttgcgatc ggcgtgaagc ctattttgct tgcaaagcct
8281 atttttagta gtgataaatt taatatcaat gatgaaaatt tcaagaattt tttgactcca
8341 gctagaaata tggagccaaa atttaatcta aattctactt tttttcttca aacttcaggc
8401 tcgactggaa atagcaaaaa tatcccaaaa agacttggtg cgatgataga agaagggcta
8461 tttttaaaag aagaacttgg agttaatgaa agcgatacat ttttttcaag cgtttcacat
8521 cagcatatgt ttggccttac ttttaaggta tttttgccca tcatctctgg tgcaaaggtt
8581 gttagtaggg agctaaatta cccagaggcg atctttgagc tagagcttga aaatttaagt
8641 ttcataacaa gcccagtttt gcttcaaacg ctaatttcta gcccaagagc agctgaaatt
8701 ttagggctaa aaaacatcat ctgtgccggc tcagccctaa agagcgagct aagagctagc
8761 atagcaaaac taagcagtgc gtgcatcatc gacatctatg gcagtaccga aactggtgta
8821 gtggctagaa atttaggtga tgaacttttg ctttttagca aggtaaaggc agatcttagc
8881 gaggacgagg cattaaacgt gagttcgcca tggtgtgagt ttttccaaac tagcgactgg
8941 gcacagataa atggcaacag actcacgcta aagggcagga tcgataggat agtcaagcta
9001 aatgacaaaa gggtcaatct aataagcatc gaaaataaga tgcttgaaag tggcctttta
9061 aaagattgct actgtgatac gcatccaaaa tttaagcgcc tagccgcact tttagagctt
9121 agcgaagagg gtgtgaagct ctttagagat agcggcaaaa agggcgttgt agcaaggcta
9181 aatgagcttt taaggcctga gtttaaaaat agtgttaggt attttaaaat cgttagctca
9241 ctttgtaaaa acgcacaagg taaatttata aaagcaaatt ttaaagagct tttagaaaag
9301 attggggagc ctagttggga taaaagtagt gaaaatggca tctacaaatt taaaacaaag
9361 cttagcccag cacttggtat ttttaccgag cattttccaa atttaccgtt gctacctggc
9421 tttgtgcagc ttgattttgt atttaaattt gcaagagagc ttggcgcaga aataggcgat
9481 cagtgcgtgg tagagaatct gaaattttta aaatttgtaa ggccaaatga cgagcttcgc
9541 atagaaattt cgcaaaaaga tgagaaggtt tattttgaga tattttgtaa cggtgctaga
9601 agtgctgctg gtaggataaa gctgggctta tgaagacgct ctttctcata ccattttaca
9661 accatccaga gaagatcaaa gccctttgtg aggcgcttgc tagctatgat ctacctattt
9721 taatagttga tgatggctca aatgagactt caaaaaaagc tttgcaaaat ttgagcgaat
9781 ttggtgtaga aatttttaca agagcacaaa acggcggtaa gggagctgca ctaaaagatg
9841 gctttaggca cgctgtgcaa aatggctaca cgcatgcatt tcagatcgac gctgactttc
9901 agcacgacat aagcgaagtg actgagtttt tagagcttag cagaaagtat ccatacgata
9961 tgataatggc tgatcctatc tatggcgagg atgcgccaaa gtctagattt tatggtagaa
10021 agatcacaaa tttttgggtt aaggtaaaca ccctaagcac caacataaaa gatgcgatgt
10081 gcggctttag aatttatccg ctaaaagagc ttgagagcgc gacctttcaa agtagctcaa
10141 ataggatgga atttgacatg gagatcctag taaatgctgt gagagcaggc attagactaa
10201 agtggatacc attaaaggta agatatgaaa aaggtggaat ttctcacttt aaaatgctag
10261 aagataacgt attaataagc cttatgcatg caaaatattt ttttagtttg gttccatttt
10321 tgctaggtaa agcctttaaa gggcaaaaat acgtatggtg gcaaaaaggc gaaagatcaa
10381 atgaattttt cttaagggtg agtttatttt taaccaagaa tttgcctatt tttcttataa
10441 agcctatcgt tatgatcgtc gtttgttttt attatatttt ttcaaaaata gagagaaaaa
10501 atataagaga atttttacaa aatgtagaga aatttagtgg taaaaagccg actactggtg
10561 tttttagaaa tttttatgaa tttggtattg ctatttgcga taaatttcgt atttggcaaa
10621 atggtgtgct cgaaaatgaa ctagatattg acgaacttat gtggataaaa gaagagtttg
10681 aggcatcaaa gcgtggcagg attttgctaa caagccatct aggaaatgta gaaatttgca
10741 agacactttc gcttagatcg ccaagttttc gtatgatcat cttggtttat agtaagggaa
10801 atgaaaattt ttataaaatt ttagagcaga taagtaaggg gcagatcaaa ctaataagcg
10861 tagaaaatct cgatgcagca gctatgcttg atctaaaaga ggcggtagaa ggtggcgtaa
10921 atatcggcat aatgggcgat agaactccgg taaatggcga taaatttgtt gaggttagct
10981 ttcttggcaa gatggctaaa tttaactatg gcccatactt actagctggc attttgggtg
11041 taaaaatgag cacgctttgg tgcgtaaaaa atggcgataa attcagtatc gagctaagtg
11101 acatcgcaga tgagataaaa ctaggtcgcg accgcaaggc aagcgtcatg ccatacgtgc
11161 aaagctatgt aagacagctt gaggatcacg cttgcaagaa cccatcgcag tggtttaact
11221 tttttgactt ttggagataa atttgaaaat ttcacacgtt agcacattta aagtggcgtt
11281 ttttgatgtt gatagcatgg aagtgatgtg gcatggtaac tatgtcaagt acctagaaat
11341 ggcgcgctgc gagctacttg acaagctagg gtacaactac attgctatga aaaaagatgg
11401 ttacgccttt cctatcgtaa agcttgacgt aaaatacgtg cgcccagcct tttttaacga
11461 cttcataaag gtcacaacga cgcttagcga gtgcgaaaca tttttaaaat ttcactatct
11521 tatagaaaat gaaaagggcg aaaagctaag tgaggcaaat accgcgcaag ctgtcatcga
11581 tatgaagagc ttacaaactt gctttgagat gcctgaatcc ttaaaaaaag cgattgaagc
11641 ttacacgaaa aaggaaaatt tatgaaaaaa ataactcttt ttttagccat ttttatatct
11701 tgctttggct atgagctaag cgagcttaaa aatatagtaa aaacagatgg tgtaggcgga
11761 aatttcacgc agacaaagag cctggctggc tttaacaaaa gcataaaaag cacaggtgag
11821 tttaggctag aaaaggacgg tctttactgg gatacgctag agcccgtcgt ctcaaaggtt
11881 tttataaaca aagatggtat ttttaaaaac gaaaatggca agcttgaaaa gacaactgca
11941 aattttgacg aaaagctatt ccttgctatc atcagcctag atgagagcga gcttagaaaa
12001 gaatttgaca taaaaacaag cggcagccta aaagagtggg aaatagagct aagccctaaa
12061 aatttactct ttaaacaaat ttttaaaagc ataaagataa gtggcgacga tgtggtaaaa
12121 aagatcgagc ttgacgaggt aagcggagat aaaacaataa atgagtttag tctaaaatga
12181 aaaaactagt cacgatcttg gcttttatct ttgttttttt agcctcgctt ggatattcgc
12241 ttgcgagcct aaaaaacgtc caaaccgaca tcttttcact gataaatttc aaagacgcca
12301 aagaggcaaa ggtgctaaaa gaggtgcaag atgagatggc gtcaaatttt ttagtgttag
12361 taaattccaa agagctagcc aaaaatgtgc aaagcttagc ttttaaaagt tcccttttta
12421 agagctttga ggcgaacatt gacgtaaatt taaatgatat aaaaaacgac atcaaccgct
12481 caaagatcgc gcttttaagt agggctgatc tagagctttt aaaaagcgat aaaaacgcct
12541 ttttcaaaaa gcgcgcagag gaaattttta acagttttag ctttatgctt ttaaatgtaa
12601 aagatgattt tttctcgcta agtagtggtt ttagtgcaaa aaacggcaat gttagcttaa
12661 atttagcaga tctaatgctt gaggtaaagg acagagagag gagctttttc ttgctaaaag
12721 gcgagctaaa aagtggcgtg ggaggtgagg ggctaataaa attttataac gagttaaatg
12781 cgctaaaagt tggacaaaac gagctttttg tgcactcaag tgccctatat caggcatttt
12841 caaagcaaaa aaatgagagc gagagccttt atatgagcgt ggtctcgctt agtttgaccg
12901 ctatattttt gatgcttgct tttagaaatt tgcgaatttt ttatgtgata tttatcgctg
12961 catttggctt tagcttggca tttgcaggca ctttactctg ccttggtgag ctaaatatcc
13021 ttactatttt aataagcaca agcctcattg gccttatgtt tgactacgtt ttacactggc
13081 ttagtaaaaa cgagggcgaa gcgatcagga cagacagcat aaaaaacatg ctaaaaattt
13141 ttttgttagg cctatttata acgcttagtg gctatctggc ttttactttt tctgatctta
13201 ggctgcttaa agaggtggcg ctattttcgg cgtttgcact tgttgctgcg tttttggcta
13261 gctacttttt catacctttg gtctttgaag gggtgaaatt ttatagatca aagctctttg
13321 ataggttttt aactaaattt tgcaagctct ctgccctagt tgctaggcat ttgggggtta
13381 aatttctagc tttttcgctt attttgctag ctatttttat cgggcttgat cttaaaaatt
13441 tatcaaaaag tgaaaacgta aaagactact caaatatgcc aaagagcctg ctagcgaact
13501 cttcttatat cttaagccta actggcaaca accaaaatac tatgatcgtg acaagatctg
13561 gtggcgacat tttgggtgat gaaaagagcc ttttagatga gctaaaaaag agaaatttga
13621 taaaagatga gagctcgcta agtgatatgt ttttaagtaa aagtgagcag ggtgagctaa
13681 aagaggtgtt taaaaaggtg cttgatgatg agcaaattta tgcggtttat gagaaatttg
13741 gctttaacaa agatgagata agggatgaaa ttttaaaaat tttgggcgaa aaagagcttg
13801 gcgtgagtga aattttggct ctaaaatcaa tgaaggattt taagaaattt atgcttgatg
13861 aaaatgcaag tgtggcttac gcgagtggct ttgtaaaagg agcggcaagt gatgatgtgc
13921 tagagcgcta caacgctttt agtctaaatt ttgctagctc gctaaatgag agcctaactc
13981 aggcaaaaga gcttgctcta aagctaaaaa tagcagcact tgtgatcgca tttttactgc
14041 tatggtttta ctttagtgcg cttatctcgg cacttgtgat gggcaccatc gtctttggcg
14101 tgcttcttac gctctttatc tttgccgttt ttggcataaa tttaagcatc tttggtgtct
14161 ttgggcttat acttgcaagt gctgtgggga ttgattacat gatatttgcg ctaaatgaga
14221 gccttagcga aaaagagcga atttatggga tattttgcgc atttatcacg agttttatct
14281 cgttttttac cctctctttt agtcagaccg ccgctcttag cgtctttggg ctaagcgtta
14341 gcctttgcgt gctgatatat gggctatgtg ctagcgtttt ggcttgtaaa aatataaaaa
14401 tttagctttg ttttcacgcc ccaagcgttt tggctagctt ggggctttgg tgatattatt
14461 ttatgacggc tagtttgcct gtgccagcgt tttgatttac ctctttttgg acatttgaag
14521 cttcgaggag ctcaaattta tatggaggct caaatggtgg tttgtctagc ttttcgcaaa
14581 cgctgccctt tttagaaagg tctatgttgc cgctttcaaa aatggtgcct ttgttacatt
14641 tgtagcttat cttgacgcca tttgtaaagt agttgttttg agcgtatact agcgagccaa
14701 agcgcactcc aatggcgtat ttttggtcat aaaagccatc ttttgagtcg taaaagttgt
14761 tatagacgtg cacctttgca ttgcgtgcca taggtaggcg ttgcgcgcag ttgtcaaaaa
14821 tgttatgagc gaccgttata gttctcgttt cgctgctgcc gtccgagtct cttgagccta
14881 ttagcatcgt tttgtcgtgg ttttcaaaga tgttgtgcga gatcgtgata gccgcactat
14941 cccccttgat gtcgcatagt ccgtcatagg tttgccattt agtaagctct ccgcctgcta
15001 aatgcacatg gctaagatcc acagtgtcct taaaatggca gtgatctatc cagatgtttt
15061 tgcttgattc tatgctaatg ccgtcatatt gcgcgttgaa gccgtcattt ttttgtatat
15121 ctggaaatgg atcaaaagca tcttcgacca acatgttgcg gatcgcgata ttttggacat
15181 tttttagcaa aagtgagcca ccttttatgc ctgagttttc gcctaggccg attatcgtgg
15241 tattgctagc taccggcact acgatgagct ttttgtattc gttggctaaa tttttgcgaa
15301 gcgctgctag ctttggatct tgcgaaccat ctaaatttgc atggcatgaa gcgccgtaag
15361 cctgcataaa tttagtataa gtgtcaaact cgccaccgct aatctcactc ataaatttat
15421 ccagccccaa gctattgcca ttttgcggta tcttgccttc gctaaggtct atgagcccat
15481 ccacatagat gacgtaacca cccatttgag cgtattttac gagttcttgt ctatctttta
15541 cgactacttc tttactctct ttgccggcgt atccgccaaa attttgctct gctccaatgc
15601 tagcgtaacc aaaaggcaag tcacttgctt ttatctcgcc cacctgtgcc tcagcgccaa
15661 atgcaaataa cgaagaaacg gctagaaaca atatcttttt aaacatcttt agcctcctaa
15721 atttggcttt ttatttttga tcttctgcta gaaaatcgct gccgaatttt attttggctc
15781 attaaattta gcgtaagact tttataaatt tttagtaaaa gcgaaatttt acgcgaaaaa
15841 tatctcactt tttaagcgaa gtaggcatag atacgcactt agcacgcttt gctctctaac
15901 gtagttgcgc tcccctttta aaagcagtct ctcaacctcg atgttgccgt ttctatcgcc
15961 agctgcgaca tataccgtgc caactggctt gctagctgtg cccccacctg gtcctgctat
16021 accgctaata gcaagtgcaa agtccgcatt tgtcgtgctt agcgtgcctt ttaccattgc
16081 ttttacgcaa ggctcgctca cggctccgta agtatctaaa atctcatcct caacgcccag
16141 ccactcgtgt tttatgtggt ttgcataagt caccaatgag ccatcaaagc tagccgagat
16201 gccgccatat cttgcaaatt tagccgctac aagcccagcc gtgcaagact cagcaaatga
16261 aattttaagc ccattttgca tgagcttttt tgctacaaat ttgatcacat ctttttgcgg
16321 gataaatttt tgcgaaaata gcgtttttac cccttgtaaa aagctctcga tctggccaaa
16381 tttattgctt tttgccctta ctagtatcaa atttggcagg atctgcgcaa gagtgatatc
16441 gacctcataa gttttagcaa gtggtagcat aaggatcttc gcgctatctg cgtcgatgtc
16501 tattagatga aagtagctaa aatcaggctc atagtcggtt agaaactcgc ctagctcttc
16561 atttggatta gcttttataa gatttatctg ggcgttattt agactggcta aaaagctatt
16621 tttagagtag tctaagctat ctttaagcgc aagtgtcgtg ctatctttta gctcgagcga
16681 gcccccagtt agcgtcgcta ctatctttgc agcgatggca aaattttcat ccgagccaaa
16741 aatgcttaca aagtcgtaat tttttgataa attttcgatg ataaaaggta gctctttgct
16801 attttttgga gcaaaactga ccactccaag ctcgccaaaa tgatcctcgt agctttgaaa
16861 aatgtagttt agaaattctc tatttatctc aagatcttcg cctattatca agatactttg
16921 tctcattttt aagctccttt ttttgcctca ttatactatt tttcagtgtg atttaaccag
16981 cacaggtgta aaattagcaa attttaaaat caaggtaaaa aatggactac aaagagacac
17041 ttttactccc agagacaaat ttcccgatgc gcggaaatct cccacaaaat gaaccgcaaa
17101 gactaaaatc atggtacgaa gagcgcaagg tttatgaaaa aatgaagaaa aatcgccaaa
17161 atgcggttaa aaacttcaac atccacgacg gccctccgta tgcaaacggc caccttcaca
17221 tcggccacgc gttaaataaa attttaaaag atatcatcac aaaaacgcac tatttttacg
17281 gcgaaaacgt ccgctatgtg ccaggctggg attgccatgg cttgcctatc gagcaacaag
17341 ttgaagtaaa gcttggcgat aagaaaaaag atcttagcaa ggtcgagatc agggagcttt
17401 gcaggcagca cgcaagagaa tttatagata ttcagcgaaa tgaatttaaa agccttggca
17461 tcatcggcga ctttgaaaat ccatacatga cgatgaaatt tgagtttgag gctgacatct
17521 acaaagcact ttgcgagatc gctaaaaagg ggcttttggt agaaagaagc aaaccagttt
17581 attggagctg ggcagctaga tcggcgctag ctgaagctga ggttgagtac gaggagaaag
17641 aggactactc tatttacgta gcatttgagc ttgacagcga cgcgctagaa aagcttggtg
17701 taaaagaggc aagcgctgtt atttggacga ccacgccttg gacacttcca gcaaatcaag
17761 ccataagcct aaaaccagat gaaatttacg tactaacagc cgaaaatttg atctttgcaa
17821 agccactact tgaaagcgtt gtacaaagcg gcctaagcaa gggcgagatc aaaaaagagt
17881 ttaaatcaag cctgcttgaa aacactcacg cgataaatcc actaaacggc agaaagtcac
17941 gatttttact aggtgatcac gtcatgatgg acggaggtac tggacttgtt catacagctc
18001 caggacacgg cgaagacgac tactacgtct gtttgaagta tggctttagc gaaattttga
18061 tgccagttga tgatggtggc tgctacgatg agagcctaaa acatcacgga ctatttagaa
18121 gcgacgtggt agacgagttt gttggcatgc acatctttaa agcaaatgag aaaattttag
18181 agctacttgg caaaagcttg cttagcgtct ctaaatttag acactcttat ccattctgct
18241 ggagaacgca taagcctgtt atttatagag ccacaaagca gtggtttata gctatggatg
18301 aggcaaaact aggcggaaaa acgcttagac aaacagcacg cgaggagctt gaaaaggtta
18361 aattttatcc aagcgttggt ataaaaagaa taggctcaat gatagaaaat cgcccagact
18421 ggtgcatctc acgtcagcgt gactggggcg tgccgatcgc gttttttaga gataaagcga
18481 caaaagaagt tatatttgat agtgaaattt tagaccacat cgtggctatc tttaaagaaa
18541 aaggcgctga tgcgtggtgg gcgctaagca tagacgagct tttgccaaag ggcacaaaat
18601 acaaggctga aaatttagaa aaagtgatgg acatccttga tgtttggttt gatagcggct
18661 cgacatggca tgcggtctta caaagtgaca actacgacgc tggcaaatac cctgcaagca
18721 tgtatctaga gggctcagat cagcaccgtg gctggtttca aagctcgctt ctagtaagca
18781 cagctataaa ttctcacgca ccttacgaga gtatcctaac tcatggcttt actgtcgatg
18841 ctaagggcga gaagatgagc aagagtaagg gtaacgtcat cgctccacaa gacgtggcta
18901 agactcacgg agtggaaatt ttacgccttt gggttggtat gagtgattac tcaagcgacc
18961 taaaaataag cgaagatata ttaaaacaaa taagcgagca gtaccgcaaa attcgcaaca
19021 ctatccgctt tttactagca aacgtaaatg accttgagag cctaaataca gagtttaaca
19081 tccttgataa atggatatta gctcgtgcta aaaaggtctt tgatgaggcg agctcttgct
19141 ttagaaacta cgacttttca aagggcttta acatcctttt aaatttctta tcagccgatc
19201 ttagcggtgt atatcttgac gtttgcaaag atagacttta ctgcgacgca aaagacgccc
19261 caagaagaag atcagcccaa agcgcaatgg cgatcataac aaaggcactt ttgccactca
19321 ttgctccaac gcttacttac accgtcgatg aggtgatgga ctacgctcca aagatcatca
19381 aaggcgaggc aaaagacgcg tttgatctag tttatgagcc aatcaaattt gaccttagct
19441 ttgaagatga gctacttttt gccagcaggg agaaatttaa cgagatcgtg gacgttctta
19501 aaaaggacaa aaagataaaa tcaactctgg agctaagcct agagacaact aaccacaaca
19561 tcacaggcta cgacgagcgc gaagtggccg atctttacat ggtaagctcg gttaaagctt
19621 atgatgatag cgagccatta gccgagtttg agctagaggg tgataaattt aagatcatag
19681 caagcaacct tcacaaatgc ccaagatgct ggaaatttaa cgctagcaaa gaagatgcgc
19741 tatgcccaag atgtgaagag gtcataagtg ctaagtgagc cagtaagcgc aactatcata
19801 atagcaacga tcgctgcggt ggtcgttgtt agcttgtttg gcatattttt ggttaataaa
19861 tttaaaggat aaaaatagtg gtaactttaa aagaagcttt gaaattttca gctgaagaga
19921 taaaaaattt aagagccgag cttgaggcga agatcataaa agaaaaagag cttggtgctt
19981 atgtcgagca gctagcaaat ttagagatcg caaaactagg cgagggcgtg cctatcgcta
20041 taaaagacaa catccaagta aaaggctgga gcgtcacgtg cgcttctaaa attttacaag
20101 gctacgtagc accatataat gcaaccgtta tcgagaagct acttagtaaa aatttagctc
20161 catttggccg cacaaatatg gacgaatttg cgatgggaag cacgactgag agctcatttt
20221 acggcaaaac actaaaccca ttaaatcacg ctcacgtccc aggtggcagt agcggtggct
20281 cagcagcagc agtcgcagct ggccttgcag tcgcagcact cggaagtgat actggtggct
20341 cgatccgcca gccagcggca ttttgtggat gcgtaggttt taagccaact tacggcagag
20401 tgagtagata cggccttggc gcatactcaa gtagccttga tcagataggc ccgatcgctc
20461 aaaacgtaga agacgcagcc attttatatg acgcgatcgc tggacacgat ccaaaagata
20521 gcacgagcgc agatgtgcct tttgagagca ttagcgacaa gatagatagc gagaagaagc
20581 taaaaatttg cgtcattaaa aactatgttg aaaatgcaag cgaacagaca aaagctgctt
20641 taaatttagc gatcgagaag ctaaaatcac atggacacag cgtaacttac acaaattttg
20701 aagactcgaa atacgatgtc gcaacctact acataatagc aaccgcagaa gcaagcgcaa
20761 atttaagccg ctatgatggc gtgagatacg gcagacgcgc agatgctaga aatttaaaag
20821 agctatatgt aaattcacgc tcagaaggct ttggtgaaga ggtaaaaaga agaattttgc
20881 ttggtacgtt tgtattaagt agcggatatt acgatgctta ctacatcaaa gcgcaaaaag
20941 caagagcaca tataaaagct caatacgaga gaattttaga agaaaacgac cttatattta
21001 tgccagtagc tccgagtaca gcctataaat ttggggccca cagtgatcca ctacaagcat
21061 atctaagcga tatttacact atcagcgtaa atttagcagg ccttccagct atctctgtgc
21121 cagttggcaa agatgatcaa aatttaaatg tgagcgccca gctcatcgca aaagcgtggg
21181 acgaacagac cttgataaat ggtgctaaga gcctagaaaa tttaataaaa ggataaaaat
21241 atgaagatag taaagagagc tttaacattt gaggatgtgc ttcttgtgcc acagtactct
21301 gaaattttgc caaagcaagt tgatgtgaaa accaggatca gcaaaaacgt cacgctaaat
21361 atcccgatcg tctctgctgc gatggatacg gtgactgagc atagaactgc tattatgatg
21421 gcaaggcttg gcggtatcgg cgtaatacat aaaaatatgg atatagaaag ccaagcaaaa
21481 gaggtcaaac gcgttaaaaa aagcgaaagt ggcgtcatca tcgatcctat ctttataaat
21541 ccagaagcga ctgtggctga agctctaagc cttatgtcag atcttcatat ttcaggcgtt
21601 ccagtcatcg acaaagaccg caaactaata ggaattttaa caaaccgcga tttgagattt
21661 gagacaaata tgagcacttt ggtaaaagac cgcatgacaa aagcaccact tatcactgcg
21721 ccaaagggct gcacgcttga tgatgcggag aaaattttct ctcaaaacag ggttgagaag
21781 ctacctatcg tcgataaaga cggcagactt gacggactta tcaccataaa agatctaaaa
21841 aaacgtaaag agtatccaaa cgcaaacaaa gatagctacg gcagacttcg cgtggctgcg
21901 gctattggcg tgggtcagat agagcgcgct aaagcgctag ttgatgctgg cgtagatgtc
21961 atcgttatcg actcagctca cggccactca aagggcatca tcgacacttt aaaagaggta
22021 aaagcaaatt ttaatgtcga tgtcatagct ggtaatatcg caaatccagc agccgtaaaa
22081 gacctagtag aagcaggagc ggacggcata aaggtaggta tcggaccagg ttctatttgt
22141 accacaagga tcgttgctgg cgttggcgtg cctcaaattt cagctatcga tgactgcgca
22201 agcgaagcag cgaaatatgg catcccagtt atcgcagacg gcggactaaa atactcaggc
22261 gacgtggcaa aagctcttgc agcaggcgca gcttgcgtta tggctggtag cttgctagca
22321 ggttgcgagg agagcccagg cgagcttata acattccaag gtcgccagta taaagtatat
22381 cgcggtatgg gctcaatagg cgctatgaca aagggtagct cggaccgcta ctttcaagag
22441 ggcaccgctc aagacaagct tgtacctgaa ggcatcgaag gccgtgtgcc atttgctggt
22501 agcataaaag atgtgatcca tcagctaata ggcggcctaa gaagcgctat gggctatgtc
22561 ggcgcaaaag atatcccaac tcttcaagaa agagctgaat ttgtcgagat aacaagcgca
22621 ggactaaaag agagccacgt ccacgatgta gttatcactc acgaggcacc aaactacaaa
22681 gttaattagt gttagacctg cagactagaa ctattaaatt taacgagcca ctctatcttg
22741 agagtggccg tatactatca aattttaagc ttatttatga gacttatggc acgttaaatg
22801 ccgataaaag caacgttatt atcatctgcc acgccctaac tggctcgcac cacgcagctg
22861 gcacctacac aggcgatgag aaagctggct ggtgggacgg gctaataggc agcaaaaagg
22921 cggtcgatac ggataaattt tacgttattt gcgtaaatat cttaggctcg tgctttggct
22981 cgacctcgcc gctaagtgtt gatagaagta gcggcaaaga gtataggcta aatttcccag
23041 tccttgccat aagtgacgtg gtaaaggcgc agatgaggct atttaacgag cttggtatca
23101 caagagcaag agctgtgatc ggcggtagtc ttggcggtat gcaagcactt tgctacgcta
23161 tcgagtttcc agaatttgcg caggatatca taatgcttgc aagtacctat cagacgaagc
23221 cctgggcgat agcttttaac aaaatcgcca tcgaagccat tttaaacgat gaaaatttca
23281 aaaacggcga atacgacgtg gaatttataa gaaaaaatgg gctaaagggt atggcttacg
23341 gcaggatggc agggcacatc agctttttaa gccctgatag catggatgag aaatttggac
23401 gaaactacgt agaaactgac ggtctttatg agctttctgg gcgctttcag gtggatcgct
23461 acatggagta caacggctac aacttcccaa agagatttga tccgctaagc tacctataca
23521 tcgtaaaaat gatgaatatt tttgactgta ctaggcacta tgataattta aaagacgccc
23581 ttgtgccgat caaagcaaac ttgcatttaa tcgctttcaa aggcgatctg ctctttccgc
23641 cgtgttgcat gagagagatt tatgatacgc tttgtgagat ggggcgagga gagaatacaa
23701 atttcgtaga gatagatagc aactatggcc acgatgcatt tttggtcgag atagaaaaat
23761 ttgatggata tataaaaaat atattaaaag gatagagaat ggagcaaaaa gagcaaagct
23821 ttgaagaaaa attagctcta gcagataaaa ttttaaacga tctaaacaaa gatgatgtga
23881 gcttagaaaa tagcataaag ctgcacgaac agggcaaaaa gctactaaat gaggcaagag
23941 aaattttaga aaacgcaaaa cttagcataa agcaggtgga tgatgagtag aatttgtgct
24001 cttcagctac caacgcagcc tttaagtgag gcaaggcttg attattatct aaaaatttgt
24061 gcggacgaaa acgcaagact tgttgtgctt ggtgaatatg tgctaaatag cttttttaaa
24121 gagctcatta gcatgccaaa aagccttata aaagagcaaa gtgagcgcaa aaaagaggct
24181 ctttttgcaa tggcaaaaaa gtatgatcta aatatcgttg cacccattgt aaatctaaaa
24241 ggcaaggaaa tttttaaaag tctagctaaa tttaccccaa cacaagtcaa attatatgat
24301 cagcaaattc tcatgcctta cgctcactgg aatgaggcga aattctttaa taacacaagc
24361 gatgagctaa atttgcctat ctttacctac gataaattta aggtcggcgt catgtttggc
24421 tatgaggcgc actttgatgt gtgctgggcg tatatgagcg ctaaaaaggt tgatatcgta
24481 ctcgtgccaa cggcttgtac atttttctcg caggcgcgct gggaggagct tttaaaggtt
24541 agagccttta caaacaacgt ctatgtgctg cgcgtaaacc gcgtaggaag ccataaaagt
24601 gaggatgcgc agtggagctt ttacggcgat tcgatgctta ttaatccgtt tggtgaagtt
24661 aaaaatagac tcggcaagaa cgaagagatg atgatcgatg agcttagcaa aaaggagctt
24721 agcgaggcta gaagcacttg gggttttatg cagatagagg cgaaatttaa aagataaaat
24781 aaggccgtaa ctggatgaga aagtgagctt agcaagaatg agcgctcttt aaaggaattt
24841 tggagtgaaa tttgaaacga agcgagattg aaaaatatat aaaagagaaa tttgacattt
24901 taggggagca actttttcca aagtatccaa attttagtgc ctttcgtcac aagaaaaaca
24961 aaaagtggtt tgcgctactt atgcagttaa gcgctagcaa gctaggtctt aaaagtgacg
25021 agatgattga ggttttaaat ttaaaatgta gtccagatct agccatggtg ctagttgatg
25081 agaggcaaat ttttaaagca tatcacatga ataaaaagca ctggataagc gtaaatttaa
25141 actcaaaaat ctcacaaaaa acagtttttg acctgataga cgagagcttt agcttaagca
25201 aataaaagcc attttcaggc ttaaatttag t
//