HRGM_Genome_3868 - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

c00001_HRGM_G.. (original name was: HRGM_Genome_3868_1) (Genus species)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS,sactipeptide	276,547	332,658

c00006_HRGM_G.. (original name was: HRGM_Genome_3868_6) (Genus species)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	bacteriocin	12,293	22,571

c00018_HRGM_G.. (original name was: HRGM_Genome_3868_18) (Genus species)

Region	Type	From	To	Most similar known cluster		Similarity
Region 18.1	NRPS	1	20,688

Region	Type	From	To	Similarity
Region 1.1	NRPS,sactipeptide	276,547	332,658
Region 6.1	bacteriocin	12,293	22,571
Region 18.1	NRPS	1	20,688

No secondary metabolite regions were found in these records:: c00002_HRGM_G.. (original name was: HRGM_Genome_3868_2) (Genus species); c00003_HRGM_G.. (original name was: HRGM_Genome_3868_3) (Genus species); c00004_HRGM_G.. (original name was: HRGM_Genome_3868_4) (Genus species); c00005_HRGM_G.. (original name was: HRGM_Genome_3868_5) (Genus species); c00007_HRGM_G.. (original name was: HRGM_Genome_3868_7) (Genus species); c00008_HRGM_G.. (original name was: HRGM_Genome_3868_8) (Genus species); c00009_HRGM_G.. (original name was: HRGM_Genome_3868_9) (Genus species); c00010_HRGM_G.. (original name was: HRGM_Genome_3868_10) (Genus species); c00011_HRGM_G.. (original name was: HRGM_Genome_3868_11) (Genus species); c00012_HRGM_G.. (original name was: HRGM_Genome_3868_12) (Genus species); c00013_HRGM_G.. (original name was: HRGM_Genome_3868_13) (Genus species); c00014_HRGM_G.. (original name was: HRGM_Genome_3868_14) (Genus species); c00015_HRGM_G.. (original name was: HRGM_Genome_3868_15) (Genus species); c00016_HRGM_G.. (original name was: HRGM_Genome_3868_16) (Genus species); c00017_HRGM_G.. (original name was: HRGM_Genome_3868_17) (Genus species); c00019_HRGM_G.. (original name was: HRGM_Genome_3868_19) (Genus species); c00020_HRGM_G.. (original name was: HRGM_Genome_3868_20) (Genus species); c00021_HRGM_G.. (original name was: HRGM_Genome_3868_21) (Genus species); c00022_HRGM_G.. (original name was: HRGM_Genome_3868_22) (Genus species); c00023_HRGM_G.. (original name was: HRGM_Genome_3868_23) (Genus species)

Compact view

c00001_HRGM_G.. - Region 1 - NRPS,sactipeptide

Download region GenBank file

Location: 276,547 - 332,658 nt. (total: 56,112 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
sactipeptide: (subtilosin or thuricin or TIGR04404 or TIGR03973)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Sactipeptides

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

Sactipeptide predictions

Sactipeptides - No core peptides found.

NRPS/PKS products

NRPS/PKS monomers

Sactipeptides

Predicted core structure(s)

For candidate cluster 1, location 276546 - 332658:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 276546 - 323824:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

HRGM_Genome_3868_CDS_00277

Search NORINE for peptide: strict or relaxed

AMP-binding (440..828): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAmfsGAIfK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 60% (weak)

AMP-binding (1443..1842): X

NRPSPredictor2: gly, ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DfmSDgGIsK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 60% (weak)

Core peptide predictions

No core peptides found.

c00006_HRGM_G.. - Region 1 - bacteriocin

Download region GenBank file

Location: 12,293 - 22,571 nt. (total: 10,279 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

c00018_HRGM_G.. - Region 1 - NRPS

Download region GenBank file

Location: 1 - 20,688 nt. (total: 20,688 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 20688:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

HRGM_Genome_3868_CDS_01837

Search NORINE for peptide: strict or relaxed

AMP-binding (437..825): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAmFsGLVcK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)

AMP-binding (1457..1847): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMKnLGtVsK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 70% (weak)