HRGM_Genome_2249 - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

c00016_HRGM_G.. (original name was: HRGM_Genome_2249_16) (Genus species)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	T1PKS,NRPS	1	39,054

c00017_HRGM_G.. (original name was: HRGM_Genome_2249_17) (Genus species)

Region	Type	From	To	Most similar known cluster		Similarity
Region 17.1	arylpolyene	1	32,256

c00041_HRGM_G.. (original name was: HRGM_Genome_2249_41) (Genus species)

Region	Type	From	To	Most similar known cluster		Similarity
Region 41.1	thiopeptide	1	21,236

Region	Type	From	To	Similarity
Region 16.1	T1PKS,NRPS	1	39,054
Region 17.1	arylpolyene	1	32,256
Region 41.1	thiopeptide	1	21,236

No secondary metabolite regions were found in these records:: c00001_HRGM_G.. (original name was: HRGM_Genome_2249_1) (Genus species); c00002_HRGM_G.. (original name was: HRGM_Genome_2249_2) (Genus species); c00003_HRGM_G.. (original name was: HRGM_Genome_2249_3) (Genus species); c00004_HRGM_G.. (original name was: HRGM_Genome_2249_4) (Genus species); c00005_HRGM_G.. (original name was: HRGM_Genome_2249_5) (Genus species); c00006_HRGM_G.. (original name was: HRGM_Genome_2249_6) (Genus species); c00007_HRGM_G.. (original name was: HRGM_Genome_2249_7) (Genus species); c00008_HRGM_G.. (original name was: HRGM_Genome_2249_8) (Genus species); c00009_HRGM_G.. (original name was: HRGM_Genome_2249_9) (Genus species); c00010_HRGM_G.. (original name was: HRGM_Genome_2249_10) (Genus species); c00011_HRGM_G.. (original name was: HRGM_Genome_2249_11) (Genus species); c00012_HRGM_G.. (original name was: HRGM_Genome_2249_12) (Genus species); c00013_HRGM_G.. (original name was: HRGM_Genome_2249_13) (Genus species); c00014_HRGM_G.. (original name was: HRGM_Genome_2249_14) (Genus species); c00015_HRGM_G.. (original name was: HRGM_Genome_2249_15) (Genus species); c00018_HRGM_G.. (original name was: HRGM_Genome_2249_18) (Genus species); c00019_HRGM_G.. (original name was: HRGM_Genome_2249_19) (Genus species); c00020_HRGM_G.. (original name was: HRGM_Genome_2249_20) (Genus species); c00021_HRGM_G.. (original name was: HRGM_Genome_2249_21) (Genus species); c00022_HRGM_G.. (original name was: HRGM_Genome_2249_22) (Genus species); c00023_HRGM_G.. (original name was: HRGM_Genome_2249_23) (Genus species); c00024_HRGM_G.. (original name was: HRGM_Genome_2249_24) (Genus species); c00025_HRGM_G.. (original name was: HRGM_Genome_2249_25) (Genus species); c00026_HRGM_G.. (original name was: HRGM_Genome_2249_26) (Genus species); c00027_HRGM_G.. (original name was: HRGM_Genome_2249_27) (Genus species); c00028_HRGM_G.. (original name was: HRGM_Genome_2249_28) (Genus species); c00029_HRGM_G.. (original name was: HRGM_Genome_2249_29) (Genus species); c00030_HRGM_G.. (original name was: HRGM_Genome_2249_30) (Genus species); c00031_HRGM_G.. (original name was: HRGM_Genome_2249_31) (Genus species); c00032_HRGM_G.. (original name was: HRGM_Genome_2249_32) (Genus species); c00033_HRGM_G.. (original name was: HRGM_Genome_2249_33) (Genus species); c00034_HRGM_G.. (original name was: HRGM_Genome_2249_34) (Genus species); c00035_HRGM_G.. (original name was: HRGM_Genome_2249_35) (Genus species); c00036_HRGM_G.. (original name was: HRGM_Genome_2249_36) (Genus species); c00037_HRGM_G.. (original name was: HRGM_Genome_2249_37) (Genus species); c00038_HRGM_G.. (original name was: HRGM_Genome_2249_38) (Genus species); c00039_HRGM_G.. (original name was: HRGM_Genome_2249_39) (Genus species); c00040_HRGM_G.. (original name was: HRGM_Genome_2249_40) (Genus species); c00042_HRGM_G.. (original name was: HRGM_Genome_2249_42) (Genus species); c00043_HRGM_G.. (original name was: HRGM_Genome_2249_43) (Genus species); c00044_HRGM_G.. (original name was: HRGM_Genome_2249_44) (Genus species); c00045_HRGM_G.. (original name was: HRGM_Genome_2249_45) (Genus species); c00046_HRGM_G.. (original name was: HRGM_Genome_2249_46) (Genus species); c00047_HRGM_G.. (original name was: HRGM_Genome_2249_47) (Genus species); c00048_HRGM_G.. (original name was: HRGM_Genome_2249_48) (Genus species); c00049_HRGM_G.. (original name was: HRGM_Genome_2249_49) (Genus species); c00050_HRGM_G.. (original name was: HRGM_Genome_2249_50) (Genus species); c00051_HRGM_G.. (original name was: HRGM_Genome_2249_51) (Genus species); c00052_HRGM_G.. (original name was: HRGM_Genome_2249_52) (Genus species); c00053_HRGM_G.. (original name was: HRGM_Genome_2249_53) (Genus species); c00054_HRGM_G.. (original name was: HRGM_Genome_2249_54) (Genus species); c00055_HRGM_G.. (original name was: HRGM_Genome_2249_55) (Genus species); c00056_HRGM_G.. (original name was: HRGM_Genome_2249_56) (Genus species); c00057_HRGM_G.. (original name was: HRGM_Genome_2249_57) (Genus species); c00058_HRGM_G.. (original name was: HRGM_Genome_2249_58) (Genus species); c00059_HRGM_G.. (original name was: HRGM_Genome_2249_59) (Genus species); c00060_HRGM_G.. (original name was: HRGM_Genome_2249_60) (Genus species); c00061_HRGM_G.. (original name was: HRGM_Genome_2249_61) (Genus species); c00062_HRGM_G.. (original name was: HRGM_Genome_2249_62) (Genus species); c00063_HRGM_G.. (original name was: HRGM_Genome_2249_63) (Genus species); c00064_HRGM_G.. (original name was: HRGM_Genome_2249_64) (Genus species); c00065_HRGM_G.. (original name was: HRGM_Genome_2249_65) (Genus species); c00066_HRGM_G.. (original name was: HRGM_Genome_2249_66) (Genus species); c00067_HRGM_G.. (original name was: HRGM_Genome_2249_67) (Genus species); c00068_HRGM_G.. (original name was: HRGM_Genome_2249_68) (Genus species); c00069_HRGM_G.. (original name was: HRGM_Genome_2249_69) (Genus species); c00070_HRGM_G.. (original name was: HRGM_Genome_2249_70) (Genus species); c00071_HRGM_G.. (original name was: HRGM_Genome_2249_71) (Genus species); c00072_HRGM_G.. (original name was: HRGM_Genome_2249_72) (Genus species); c00073_HRGM_G.. (original name was: HRGM_Genome_2249_73) (Genus species); c00074_HRGM_G.. (original name was: HRGM_Genome_2249_74) (Genus species); c00075_HRGM_G.. (original name was: HRGM_Genome_2249_75) (Genus species); c00076_HRGM_G.. (original name was: HRGM_Genome_2249_76) (Genus species); c00077_HRGM_G.. (original name was: HRGM_Genome_2249_77) (Genus species); c00078_HRGM_G.. (original name was: HRGM_Genome_2249_78) (Genus species); c00079_HRGM_G.. (original name was: HRGM_Genome_2249_79) (Genus species); c00080_HRGM_G.. (original name was: HRGM_Genome_2249_80) (Genus species); c00081_HRGM_G.. (original name was: HRGM_Genome_2249_81) (Genus species); c00082_HRGM_G.. (original name was: HRGM_Genome_2249_82) (Genus species); c00083_HRGM_G.. (original name was: HRGM_Genome_2249_83) (Genus species); c00084_HRGM_G.. (original name was: HRGM_Genome_2249_84) (Genus species); c00085_HRGM_G.. (original name was: HRGM_Genome_2249_85) (Genus species); c00086_HRGM_G.. (original name was: HRGM_Genome_2249_86) (Genus species); c00087_HRGM_G.. (original name was: HRGM_Genome_2249_87) (Genus species); c00088_HRGM_G.. (original name was: HRGM_Genome_2249_88) (Genus species); c00089_HRGM_G.. (original name was: HRGM_Genome_2249_89) (Genus species); c00090_HRGM_G.. (original name was: HRGM_Genome_2249_90) (Genus species); c00091_HRGM_G.. (original name was: HRGM_Genome_2249_91) (Genus species); c00092_HRGM_G.. (original name was: HRGM_Genome_2249_92) (Genus species); c00093_HRGM_G.. (original name was: HRGM_Genome_2249_93) (Genus species); c00094_HRGM_G.. (original name was: HRGM_Genome_2249_94) (Genus species); c00095_HRGM_G.. (original name was: HRGM_Genome_2249_95) (Genus species); c00096_HRGM_G.. (original name was: HRGM_Genome_2249_96) (Genus species); c00097_HRGM_G.. (original name was: HRGM_Genome_2249_97) (Genus species); c00098_HRGM_G.. (original name was: HRGM_Genome_2249_98) (Genus species); c00099_HRGM_G.. (original name was: HRGM_Genome_2249_99) (Genus species); c00100_HRGM_G.. (original name was: HRGM_Genome_2249_100) (Genus species); c00101_HRGM_G.. (original name was: HRGM_Genome_2249_101) (Genus species); c00102_HRGM_G.. (original name was: HRGM_Genome_2249_102) (Genus species); c00103_HRGM_G.. (original name was: HRGM_Genome_2249_103) (Genus species); c00104_HRGM_G.. (original name was: HRGM_Genome_2249_104) (Genus species); c00105_HRGM_G.. (original name was: HRGM_Genome_2249_105) (Genus species); c00106_HRGM_G.. (original name was: HRGM_Genome_2249_106) (Genus species); c00107_HRGM_G.. (original name was: HRGM_Genome_2249_107) (Genus species); c00108_HRGM_G.. (original name was: HRGM_Genome_2249_108) (Genus species); c00109_HRGM_G.. (original name was: HRGM_Genome_2249_109) (Genus species); c00110_HRGM_G.. (original name was: HRGM_Genome_2249_110) (Genus species); c00111_HRGM_G.. (original name was: HRGM_Genome_2249_111) (Genus species); c00112_HRGM_G.. (original name was: HRGM_Genome_2249_112) (Genus species); c00113_HRGM_G.. (original name was: HRGM_Genome_2249_113) (Genus species); c00114_HRGM_G.. (original name was: HRGM_Genome_2249_114) (Genus species); c00115_HRGM_G.. (original name was: HRGM_Genome_2249_115) (Genus species); c00116_HRGM_G.. (original name was: HRGM_Genome_2249_116) (Genus species); c00117_HRGM_G.. (original name was: HRGM_Genome_2249_117) (Genus species); c00118_HRGM_G.. (original name was: HRGM_Genome_2249_118) (Genus species)

Compact view

c00016_HRGM_G.. - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 1 - 39,054 nt. (total: 39,054 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 39054:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys) + (cys) + (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

HRGM_Genome_2249_CDS_00668

Search NORINE for peptide: strict or relaxed

CAL_domain (51..496): pk

minowa: NH2

Prediction, score:

NH2: 127.3
fatty_acid: 23.2
shikimic_acid: 0.0
Acetyl-CoA: -1.0
AHBA: -1.4

AMP-binding (2016..2415): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLfNiSMIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 80% (moderate)

HRGM_Genome_2249_CDS_00669

Search NORINE for peptide: strict or relaxed

AMP-binding (2277..2678): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLwNMSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 90% (moderate)

HRGM_Genome_2249_CDS_00670

PKS_AT (539..833): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 87.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 190.7
inactive: 133.2
Methoxymalonyl-CoA: 57.9
Methylmalonyl-CoA: 57.5
Propionyl-CoA: 41.3
Ethylmalonyl-CoA: 33.8
Benzoyl-CoA: 24.7
Isobutyryl-CoA: 22.1
CHC-CoA: 21.0
fatty_acid: 20.1
Acetyl-CoA: 19.7
2-Methylbutyryl-CoA: 17.4
trans-1,2-CPDA: 10.0
3-Methylbutyryl-CoA: 0.0

HRGM_Genome_2249_CDS_00671

Search NORINE for peptide: strict or relaxed

AMP-binding (2011..2405): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYdiSMIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 80% (moderate)

c00017_HRGM_G.. - Region 1 - arylpolyene

Download region GenBank file

Location: 1 - 32,256 nt. (total: 32,256 nt) Show pHMM detection rules used

Region on contig edge.

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

c00041_HRGM_G.. - Region 1 - thiopeptide

Download region GenBank file

Location: 1 - 21,236 nt. (total: 21,236 nt) Show pHMM detection rules used

Region on contig edge.

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Thiopeptides

ClusterBlast

KnownClusterBlast

SubClusterBlast

Thiopeptide predictions

No core peptides found.

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

Thiopeptides

Core peptide predictions

No core peptides found.